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PHF8 PHD finger protein 8 [ Leptonychotes weddellii (Weddell seal) ]

Gene ID: 102734232, updated on 10-Mar-2024

Summary

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Gene symbol
PHF8
Gene description
PHD finger protein 8
Gene type
protein coding
RefSeq status
MODEL
Organism
Leptonychotes weddellii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Leptonychotes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
101 current LepWed1.0 (GCF_000349705.1) Unplaced Scaffold NW_006383229.1 (833993..929040, complement)

NW_006383229.1Genomic Context describing neighboring genes Neighboring gene HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Neighboring gene ADP-ribosylation factor-like protein 8B pseudogene Neighboring gene centrosomal protein of 63 kDa-like Neighboring gene uncharacterized LOC115939765 Neighboring gene U6 spliceosomal RNA Neighboring gene beta-galactoside alpha-2,6-sialyltransferase 1-like Neighboring gene family with sequence similarity 120 member C

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006383229 Unplaced Scaffold Reference LepWed1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone demethylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coregulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein demethylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone lysine demethylase PHF8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Leptonychotes weddellii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LepWed1.0 Primary Assembly

Genomic

  1. NW_006383229.1 Reference LepWed1.0 Primary Assembly

    Range
    833993..929040 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031024421.1 → XP_030880281.1  histone lysine demethylase PHF8 isoform X1

    UniProtKB/TrEMBL
    A0A2U3XFA2
    Conserved Domains (4) summary
    smart00558
    Location:199 → 262
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:6 → 57
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    pfam02373
    Location:234 → 334
    JmjC; JmjC domain, hydroxylase
    pfam17811
    Location:338 → 441
    JHD; Jumonji helical domain

  2. XM_006729952.2 → XP_006730015.1  histone lysine demethylase PHF8 isoform X2

    UniProtKB/TrEMBL
    A0A2U3XEW0
    Conserved Domains (5) summary
    smart00558
    Location:199 → 262
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:6 → 57
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    pfam02373
    Location:234 → 334
    JmjC; JmjC domain, hydroxylase
    pfam03343
    Location:408 → 575
    SART-1; SART-1 family
    pfam17811
    Location:338 → 441
    JHD; Jumonji helical domain

  3. XM_006729955.2 → XP_006730018.1  histone lysine demethylase PHF8 isoform X1

    UniProtKB/TrEMBL
    A0A2U3XFA2
    Conserved Domains (4) summary
    smart00558
    Location:199 → 262
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:6 → 57
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    pfam02373
    Location:234 → 334
    JmjC; JmjC domain, hydroxylase
    pfam17811
    Location:338 → 441
    JHD; Jumonji helical domain

  4. XM_031024422.1 → XP_030880282.1  histone lysine demethylase PHF8 isoform X1

    UniProtKB/TrEMBL
    A0A2U3XFA2
    Conserved Domains (4) summary
    smart00558
    Location:199 → 262
    JmjC; A domain family that is part of the cupin metalloenzyme superfamily
    cd15642
    Location:6 → 57
    PHD_PHF8; PHD finger found in histone lysine demethylase PHF8
    pfam02373
    Location:234 → 334
    JmjC; JmjC domain, hydroxylase
    pfam17811
    Location:338 → 441
    JHD; Jumonji helical domain

  5. XM_031024423.1 → XP_030880283.1  histone lysine demethylase PHF8 isoform X3

    UniProtKB/TrEMBL
    A0A7F8QJ93
Nucleotide Protein
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