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SHMT1 serine hydroxymethyltransferase 1 [ Leptonychotes weddellii (Weddell seal) ]

Gene ID: 102733337, updated on 10-Mar-2024

Summary

Gene symbol
SHMT1
Gene description
serine hydroxymethyltransferase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Leptonychotes weddellii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Leptonychotes
Orthologs
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Genomic context

See SHMT1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current LepWed1.0 (GCF_000349705.1) Unplaced Scaffold NW_006386444.1 (74974..99658)

NW_006386444.1Genomic Context describing neighboring genes Neighboring gene phosphoribosyl pyrophosphate synthase-associated protein 2 Neighboring gene SMCR8-C9orf72 complex subunit Neighboring gene DNA topoisomerase III alpha Neighboring gene mitochondrial elongation factor 2

Genomic regions, transcripts, and products

Genomic Sequence:
NW_006386444 Unplaced Scaffold Reference LepWed1.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables mRNA 5'-UTR binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables mRNA regulatory element binding translation repressor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables serine binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in L-serine catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to leukemia inhibitory factor IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein homotetramerization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in purine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
serine hydroxymethyltransferase, cytosolic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Leptonychotes weddellii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LepWed1.0 Primary Assembly

Genomic

  1. NW_006386444.1 Reference LepWed1.0 Primary Assembly

    Range
    74974..99658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031020918.1XP_030876778.1  serine hydroxymethyltransferase, cytosolic

    UniProtKB/TrEMBL
    A0A7F8Q8X2
    Conserved Domains (1) summary
    PLN03226
    Location:19480
    PLN03226; serine hydroxymethyltransferase; Provisional
  2. XM_031020919.1XP_030876779.1  serine hydroxymethyltransferase, cytosolic

    UniProtKB/TrEMBL
    A0A7F8Q8X2
    Conserved Domains (1) summary
    PLN03226
    Location:19480
    PLN03226; serine hydroxymethyltransferase; Provisional