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TLE2 TLE family member 2, transcriptional corepressor [ Leptonychotes weddellii (Weddell seal) ]

Gene ID: 102732013, updated on 10-Mar-2024

Summary

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Gene symbol
TLE2
Gene description
TLE family member 2, transcriptional corepressor
Gene type
protein coding
RefSeq status
MODEL
Organism
Leptonychotes weddellii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Leptonychotes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
101 current LepWed1.0 (GCF_000349705.1) Unplaced Scaffold NW_006384914.1 (129653..150802, complement)

NW_006384914.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC115944716 Neighboring gene TLE family member 6, subcortical maternal complex member Neighboring gene uncharacterized LOC102732507 Neighboring gene TLE family member 5, transcriptional modulator

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006384914 Unplaced Scaffold Reference LepWed1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transducin-like enhancer protein 2
Names
transducin like enhancer of split 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Leptonychotes weddellii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LepWed1.0 Primary Assembly

Genomic

  1. NW_006384914.1 Reference LepWed1.0 Primary Assembly

    Range
    129653..150802 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006744795.2 → XP_006744858.1  transducin-like enhancer protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A2U3YMP1
    Conserved Domains (4) summary
    PHA03247
    Location:244 → 366
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:460 → 499
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 132
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:456 → 740
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_031040747.1 → XP_030896607.1  transducin-like enhancer protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A7F8RT17
    Conserved Domains (4) summary
    PHA03247
    Location:245 → 367
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:461 → 500
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 128
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:457 → 741
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_031040746.1 → XP_030896606.1  transducin-like enhancer protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A7F8RTK3

  4. XM_031040742.1 → XP_030896602.1  transducin-like enhancer protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A7F8RT12
    Conserved Domains (4) summary
    PHA03247
    Location:189 → 311
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:464 → 503
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 77
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:460 → 744
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  5. XM_031040741.1 → XP_030896601.1  transducin-like enhancer protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A7F8RTJ9
    Conserved Domains (4) summary
    PHA03247
    Location:190 → 312
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:465 → 504
    7WD40; WD40 repeat [structural motif]
    pfam03920
    Location:1 → 73
    TLE_N; Groucho/TLE N-terminal Q-rich domain
    cl29593
    Location:461 → 745
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  6. XM_031040744.1 → XP_030896604.1  transducin-like enhancer protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A7F8RUN8
    Conserved Domains (3) summary
    PHA03247
    Location:2 → 259
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:412 → 451
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:408 → 692
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  7. XM_031040745.1 → XP_030896605.1  transducin-like enhancer protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A7F8RUN8
    Conserved Domains (3) summary
    PHA03247
    Location:2 → 259
    PHA03247; large tegument protein UL36; Provisional
    sd00039
    Location:412 → 451
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:408 → 692
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  8. XM_031040743.1 → XP_030896603.1  transducin-like enhancer protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A7F8RUN8
Nucleotide Protein
Heading Accession and Version

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