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JAK3 Janus kinase 3 [ Leptonychotes weddellii (Weddell seal) ]

Gene ID: 102727785, updated on 11-Apr-2024

Summary

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Gene symbol
JAK3
Gene description
Janus kinase 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Leptonychotes weddellii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Leptonychotes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
101 current LepWed1.0 (GCF_000349705.1) Unplaced Scaffold NW_006386388.1 (158122..175071)

NW_006386388.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 5 member 5 Neighboring gene small nucleolar RNA SNORA68 Neighboring gene ribosomal protein L18a Neighboring gene insulin like 3 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006386388 Unplaced Scaffold Reference LepWed1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemopoiesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase JAK3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Leptonychotes weddellii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LepWed1.0 Primary Assembly

Genomic

  1. NW_006386388.1 Reference LepWed1.0 Primary Assembly

    Range
    158122..175071
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031020793.1 → XP_030876653.1  tyrosine-protein kinase JAK3 isoform X1

    UniProtKB/TrEMBL
    A0A2U3Z0Y0
    Conserved Domains (5) summary
    pfam18377
    Location:126 → 245
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:41 → 112
    FERM_F1; FERM F1 ubiquitin-like domain
    cl15255
    Location:362 → 458
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:250 → 362
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:817 → 1099
    PKc_like; Protein Kinases, catalytic domain

  2. XM_006749578.2 → XP_006749641.2  tyrosine-protein kinase JAK3 isoform X1

    UniProtKB/TrEMBL
    A0A2U3Z0Y0
    Conserved Domains (5) summary
    pfam18377
    Location:126 → 245
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:41 → 112
    FERM_F1; FERM F1 ubiquitin-like domain
    cl15255
    Location:362 → 458
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:250 → 362
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:817 → 1099
    PKc_like; Protein Kinases, catalytic domain

  3. XM_031020791.1 → XP_030876651.1  tyrosine-protein kinase JAK3 isoform X1

    UniProtKB/TrEMBL
    A0A2U3Z0Y0

  4. XM_031020792.1 → XP_030876652.1  tyrosine-protein kinase JAK3 isoform X1

    UniProtKB/TrEMBL
    A0A2U3Z0Y0

  5. XM_031020796.1 → XP_030876656.1  tyrosine-protein kinase JAK3 isoform X2

    UniProtKB/TrEMBL
    A0A7F8Q7Y0
    Conserved Domains (5) summary
    pfam18377
    Location:126 → 245
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:41 → 112
    FERM_F1; FERM F1 ubiquitin-like domain
    cl15255
    Location:362 → 458
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:250 → 362
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:521 → 778
    PKc_like; Protein Kinases, catalytic domain

  6. XM_031020795.1 → XP_030876655.1  tyrosine-protein kinase JAK3 isoform X1

    UniProtKB/TrEMBL
    A0A2U3Z0Y0
    Conserved Domains (5) summary
    pfam18377
    Location:126 → 245
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:41 → 112
    FERM_F1; FERM F1 ubiquitin-like domain
    cl15255
    Location:362 → 458
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:250 → 362
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:817 → 1099
    PKc_like; Protein Kinases, catalytic domain

  7. XM_031020794.1 → XP_030876654.1  tyrosine-protein kinase JAK3 isoform X1

    UniProtKB/TrEMBL
    A0A2U3Z0Y0
    Conserved Domains (5) summary
    pfam18377
    Location:126 → 245
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:41 → 112
    FERM_F1; FERM F1 ubiquitin-like domain
    cl15255
    Location:362 → 458
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:250 → 362
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:817 → 1099
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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