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RPA1 replication protein A1 [ Alligator mississippiensis (American alligator) ]

Gene ID: 102571776, updated on 10-Mar-2024

Summary

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Gene symbol
RPA1
Gene description
replication protein A1
Locus tag
Y1Q_0020523
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator mississippiensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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See RPA1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2023_09 current rAllMis1 (GCF_030867095.1) 14 NC_081837.1 (561861..584011)
102 previous assembly ASM28112v4 (GCF_000281125.3) Unplaced Scaffold NW_017714500.1 (59301..81550, complement)

Chromosome 14 - NC_081837.1Genomic Context describing neighboring genes Neighboring gene serpin family F member 1 Neighboring gene SET and MYND domain containing 4 Neighboring gene reticulon 4 receptor like 1 Neighboring gene diphthamide biosynthesis 1 Neighboring gene OVCA2 serine hydrolase domain containing

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA unwinding involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in meiotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance via telomerase IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA replication factor A complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
replication protein A 70 kDa DNA-binding subunit
Names
replication protein A DNA-binding subunit
replication protein A1, 70kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030867095.1-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rAllMis1 Primary Assembly

Genomic

  1. NC_081837.1 Reference rAllMis1 Primary Assembly

    Range
    561861..584011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006260605.4 → XP_006260667.1  replication protein A 70 kDa DNA-binding subunit

    UniProtKB/TrEMBL
    A0A151LY24
    Conserved Domains (5) summary
    cd04474
    Location:184 → 286
    RPA1_DBD_A; RPA1_DBD_A: A subfamily of OB folds corresponding to the second OB fold, the ssDNA-binding domain (DBD)-A, of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which ...
    cd04477
    Location:8 → 102
    RPA1N; RPA1N: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of human RPA1 (also called RPA70). RPA1 is the large subunit of Replication protein A (RPA). RPA is a nuclear ssDNA-binding protein (SSB) which appears to be involved in all ...
    TIGR00617
    Location:2 → 610
    rpa1; replication factor-a protein 1 (rpa1)
    pfam08646
    Location:459 → 604
    Rep_fac-A_C; Replication factor-A C terminal domain
    pfam16900
    Location:303 → 387
    REPA_OB_2; Replication protein A OB domain
Nucleotide Protein
Heading Accession and Version

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