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CHFR checkpoint with forkhead and ring finger domains [ Alligator mississippiensis (American alligator) ]

Gene ID: 102560940, updated on 10-Mar-2024

Summary

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Gene symbol
CHFR
Gene description
checkpoint with forkhead and ring finger domains
Locus tag
Y1Q_0018629
Gene type
protein coding
RefSeq status
MODEL
Organism
Alligator mississippiensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae; Alligator
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_09 current rAllMis1 (GCF_030867095.1) 10 NC_081833.1 (13040853..13066377)
102 previous assembly ASM28112v4 (GCF_000281125.3) Unplaced Scaffold NW_017709599.1 (2223604..2248444, complement)

Chromosome 10 - NC_081833.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132243466 Neighboring gene fibrosin like 1 Neighboring gene uncharacterized LOC106739023 Neighboring gene uncharacterized LOC102560702 Neighboring gene golgin A3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic cell cycle checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CHFR
Names
checkpoint protein with forkhead and ring finger domains, E3 ubiquitin protein ligase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030867095.1-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rAllMis1 Primary Assembly

Genomic

  1. NC_081833.1 Reference rAllMis1 Primary Assembly

    Range
    13040853..13066377
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019486628.2 → XP_019342173.1  E3 ubiquitin-protein ligase CHFR isoform X1

    UniProtKB/TrEMBL
    A0A151NRP6

  2. XM_006268995.4 → XP_006269057.1  E3 ubiquitin-protein ligase CHFR isoform X1

    UniProtKB/TrEMBL
    A0A151NRP6
    Conserved Domains (2) summary
    cd00060
    Location:17 → 104
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00162
    Location:318 → 361
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

  3. XM_006268996.4 → XP_006269058.1  E3 ubiquitin-protein ligase CHFR isoform X2

    UniProtKB/TrEMBL
    A0A151NS48
    Conserved Domains (2) summary
    cd00060
    Location:17 → 104
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00162
    Location:303 → 346
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

  4. XM_006268997.4 → XP_006269059.1  E3 ubiquitin-protein ligase CHFR isoform X3

    Conserved Domains (2) summary
    cd00060
    Location:17 → 104
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd00162
    Location:277 → 320
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
Nucleotide Protein
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