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RYR2 ryanodine receptor 2 [ Vicugna pacos (alpaca) ]

Gene ID: 102537530, updated on 10-Mar-2024

Summary

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Gene symbol
RYR2
Gene description
ryanodine receptor 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Vicugna pacos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Vicugna
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
109
Annotation release Status Assembly Chr Location
102 current VicPac3.1 (GCF_000164845.3) Unplaced Scaffold NW_021970132.1 (1481831..1889195, complement)
101 previous assembly Vicugna_pacos-2.0.1 (GCF_000164845.1) Unplaced Scaffold NW_005882972.1 (8504..387879)

NW_021970132.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116277541 Neighboring gene zona pellucida glycoprotein 4 Neighboring gene 5-methyltetrahydrofolate-homocysteine methyltransferase Neighboring gene actinin alpha 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ryanodine-sensitive calcium-release channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular calcium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of calcium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcolemma IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sarcoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in smooth endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ryanodine receptor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vicugna pacos Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VicPac3.1 Primary Assembly

Genomic

  1. NW_021970132.1 Reference VicPac3.1 Primary Assembly

    Range
    1481831..1889195 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031671939.1 → XP_031527799.1  ryanodine receptor 2

    UniProtKB/TrEMBL
    A0A6J3A276
    Conserved Domains (11) summary
    cd12877
    Location:730 → 881
    SPRY1_RyR; SPRY domain 1 (SPRY1) of ryanodine receptor (RyR)
    cd12878
    Location:1162 → 1294
    SPRY2_RyR; SPRY domain 2 (SPRY2) of ryanodine receptor (RyR)
    cd12879
    Location:1488 → 1634
    SPRY3_RyR; SPRY domain 3 (SPRY3) of ryanodine receptor (RyR)
    pfam00520
    Location:5051 → 5211
    Ion_trans; Ion transport protein
    pfam01365
    Location:532 → 724
    RYDR_ITPR; RIH domain
    pfam02026
    Location:938 → 1027
    RyR; RyR domain
    pfam02815
    Location:302 → 482
    MIR; MIR domain
    pfam06459
    Location:4666 → 4932
    RR_TM4-6; Ryanodine Receptor TM 4-6
    pfam08454
    Location:4168 → 4281
    RIH_assoc; RyR and IP3R Homology associated
    pfam13499
    Location:4363 → 4420
    EF-hand_7; EF-hand domain pair
    cl19745
    Location:128 → 292
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor
Nucleotide Protein
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