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SPPL2A signal peptide peptidase like 2A [ Vicugna pacos (alpaca) ]

Gene ID: 102534763, updated on 10-Mar-2024

Summary

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Gene symbol
SPPL2A
Gene description
signal peptide peptidase like 2A
Gene type
protein coding
RefSeq status
MODEL
Organism
Vicugna pacos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Vicugna
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current VicPac3.1 (GCF_000164845.3) Unplaced Scaffold NW_021988660.1 (8677842..8723831)
101 previous assembly Vicugna_pacos-2.0.1 (GCF_000164845.1) Unplaced Scaffold NW_005882786.1 (5834021..5876908)

NW_021988660.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein E pseudogene Neighboring gene adaptor related protein complex 4 subunit epsilon 1 Neighboring gene U6 spliceosomal RNA Neighboring gene 60S ribosomal protein L13 pseudogene Neighboring gene transient receptor potential cation channel subfamily M member 7 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane protein proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi-associated vesicle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lumenal side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: signal peptide peptidase-like 2A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vicugna pacos Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VicPac3.1 Primary Assembly

Genomic

  1. NW_021988660.1 Reference VicPac3.1 Primary Assembly

    Range
    8677842..8723831
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015242737.2 → XP_015098223.1  LOW QUALITY PROTEIN: signal peptide peptidase-like 2A

    UniProtKB/TrEMBL
    A0A6J0ARB2
    Conserved Domains (2) summary
    cd02129
    Location:31 → 150
    PA_hSPPL_like; Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the late endosomes, ...
    pfam04258
    Location:202 → 486
    Peptidase_A22B; Signal peptide peptidase
Nucleotide Protein
Heading Accession and Version

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