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LAMA3 laminin subunit alpha 3 [ Vicugna pacos (alpaca) ]

Gene ID: 102534754, updated on 10-Mar-2024

Summary

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Gene symbol
LAMA3
Gene description
laminin subunit alpha 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Vicugna pacos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Vicugna
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 24
Exon count:
77
Annotation release Status Assembly Chr Location
102 current VicPac3.1 (GCF_000164845.3) 24 Unlocalized Scaffold NW_021964205.1 (9462067..9668500)
101 previous assembly Vicugna_pacos-2.0.1 (GCF_000164845.1) Unplaced Scaffold NW_005882750.1 (5536368..5630694, complement)

NW_021964205.1Genomic Context describing neighboring genes Neighboring gene transfer RNA alanine (anticodon UGC) Neighboring gene NPC intracellular cholesterol transporter 1 Neighboring gene ankyrin repeat domain 29 Neighboring gene tetraspanin-17 pseudogene Neighboring gene 40S ribosomal protein S2-like Neighboring gene tetratricopeptide repeat domain 39C Neighboring gene calcium binding tyrosine phosphorylation regulated

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-3
Names
laminin, alpha 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vicugna pacos Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VicPac3.1 Primary Assembly

Genomic

  1. NW_021964205.1 Reference VicPac3.1 Primary Assembly

    Range
    9462067..9668500
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031690291.1 → XP_031546151.1  laminin subunit alpha-3 isoform X3

    UniProtKB/TrEMBL
    A0A6J3BNX5
    Conserved Domains (4) summary
    smart00136
    Location:44 → 295
    LamNT; Laminin N-terminal domain (domain VI)
    cd00055
    Location:533 → 575
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    pfam00053
    Location:1267 → 1315
    Laminin_EGF; Laminin EGF domain
    pfam16100
    Location:1060 → 1141
    RMI2; RecQ-mediated genome instability protein 2

  2. XM_031690290.1 → XP_031546150.1  laminin subunit alpha-3 isoform X1

    UniProtKB/TrEMBL
    A0A6J3BGC3
    Conserved Domains (11) summary
    smart00136
    Location:44 → 295
    LamNT; Laminin N-terminal domain (domain VI)
    smart00180
    Location:534 → 577
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00282
    Location:3014 → 3139
    LamG; Laminin G domain
    cd00055
    Location:1405 → 1455
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3161 → 3312
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:1990 → 2303
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06008
    Location:1848 → 2102
    Laminin_I; Laminin Domain I
    pfam00052
    Location:1519 → 1653
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:1267 → 1315
    Laminin_EGF; Laminin EGF domain
    pfam06009
    Location:2289 → 2417
    Laminin_II; Laminin Domain II
    pfam16100
    Location:1060 → 1141
    RMI2; RecQ-mediated genome instability protein 2

  3. XM_006205102.3 → XP_006205164.3  laminin subunit alpha-3 isoform X2

    UniProtKB/TrEMBL
    A0A6I9I728
    Conserved Domains (6) summary
    cd00055
    Location:77 → 123
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:1551 → 1702
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    TIGR02168
    Location:380 → 693
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam06008
    Location:238 → 492
    Laminin_I; Laminin Domain I
    pfam00053
    Location:125 → 175
    Laminin_EGF; Laminin EGF domain
    pfam06009
    Location:679 → 807
    Laminin_II; Laminin Domain II
Nucleotide Protein
Heading Accession and Version

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