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PKLR pyruvate kinase L/R [ Camelus ferus (Wild Bactrian camel) ]

Gene ID: 102522070, updated on 10-Mar-2024

Summary

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Gene symbol
PKLR
Gene description
pyruvate kinase L/R
Locus tag
CB1_000057011
See related
EnsemblRapid:ENSCFEG00005017070
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus ferus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
11
Annotation release Status Assembly Chr Location
102 current BCGSAC_Cfer_1.0 (GCF_009834535.1) 21 NC_045716.1 (21897072..21905333)
101 previous assembly CB1 (GCF_000311805.1) Unplaced Scaffold NW_006210233.1 (182458..191170, complement)

Chromosome 21 - NC_045716.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116658712 Neighboring gene RUN and SH3 domain containing 1 Neighboring gene farnesyl diphosphate synthase Neighboring gene hyperpolarization activated cyclic nucleotide gated potassium channel 3 Neighboring gene CDC like kinase 2 Neighboring gene secretory carrier membrane protein 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequences of wild and domestic bactrian camels. Bactrian Camels Genome Sequencing and Analysis Consortium, et al. Nat Commun, 2012. PMID 23149746, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: pyruvate kinase PKLR
Names
pyruvate kinase isozymes R/L
pyruvate kinase, liver and RBC

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Camelus ferus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCGSAC_Cfer_1.0 Primary Assembly

Genomic

  1. NC_045716.1 Reference BCGSAC_Cfer_1.0 Primary Assembly

    Range
    21897072..21905333
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006172686.3 → XP_006172748.1  LOW QUALITY PROTEIN: pyruvate kinase PKLR

    See identical proteins and their annotated locations for XP_006172748.1

    UniProtKB/TrEMBL
    A0A8B6Y6G3, S9YRV3
    Related
    ENSCFEP00005028622.1, ENSCFET00005031767.1
    Conserved Domains (1) summary
    cd00288
    Location:67 → 555
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
Nucleotide Protein
Heading Accession and Version

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