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DVL2 dishevelled segment polarity protein 2 [ Camelus ferus (Wild Bactrian camel) ]

Gene ID: 102516993, updated on 10-Mar-2024

Summary

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Gene symbol
DVL2
Gene description
dishevelled segment polarity protein 2
Locus tag
CB1_000230009
See related
EnsemblRapid:ENSCFEG00005010027
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus ferus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 16
Exon count:
15
Annotation release Status Assembly Chr Location
102 current BCGSAC_Cfer_1.0 (GCF_009834535.1) 16 NC_045711.1 (11744988..11752908, complement)
101 previous assembly CB1 (GCF_000311805.1) Unplaced Scaffold NW_006210406.1 (206050..218501, complement)

Chromosome 16 - NC_045711.1Genomic Context describing neighboring genes Neighboring gene discs large MAGUK scaffold protein 4 Neighboring gene acyl-CoA dehydrogenase very long chain Neighboring gene PHD finger protein 23 Neighboring gene GABA type A receptor-associated protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequences of wild and domestic bactrian camels. Bactrian Camels Genome Sequencing and Analysis Consortium, et al. Nat Commun, 2012. PMID 23149746, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables frizzled binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
segment polarity protein dishevelled homolog DVL-2
Names
dishevelled, dsh 2-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Camelus ferus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCGSAC_Cfer_1.0 Primary Assembly

Genomic

  1. NC_045711.1 Reference BCGSAC_Cfer_1.0 Primary Assembly

    Range
    11744988..11752908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032498618.1 → XP_032354509.1  segment polarity protein dishevelled homolog DVL-2 isoform X2

    UniProtKB/TrEMBL
    A0A8B8UIY5, T0NNC3
    Conserved Domains (5) summary
    smart00021
    Location:13 → 93
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:261 → 348
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:420 → 503
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:123 → 259
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:511 → 722
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

  2. XM_032498617.1 → XP_032354508.1  segment polarity protein dishevelled homolog DVL-2 isoform X1

    UniProtKB/TrEMBL
    A0A8B8UJD6, T0NNC3
    Related
    ENSCFEP00005016748.1, ENSCFET00005018675.1
    Conserved Domains (5) summary
    smart00021
    Location:13 → 93
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:265 → 352
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:424 → 507
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:123 → 263
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:515 → 726
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
Nucleotide Protein
Heading Accession and Version

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