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NCF2 neutrophil cytosolic factor 2 [ Camelus ferus (Wild Bactrian camel) ]

Gene ID: 102511856, updated on 10-Mar-2024

Summary

Gene symbol
NCF2
Gene description
neutrophil cytosolic factor 2
See related
EnsemblRapid:ENSCFEG00005010155
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus ferus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
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Genomic context

Location:
chromosome: 21
Exon count:
15
Annotation release Status Assembly Chr Location
102 current BCGSAC_Cfer_1.0 (GCF_009834535.1) 21 NC_045716.1 (1578851..1604285)
101 previous assembly CB1 (GCF_000311805.1) Unplaced Scaffold NW_006212092.1 (79396..104961)

Chromosome 21 - NC_045716.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene actin related protein 2/3 complex subunit 5 Neighboring gene small nucleolar RNA SNORA18 Neighboring gene SMG7 nonsense mediated mRNA decay factor Neighboring gene nicotinamide nucleotide adenylyltransferase 2 Neighboring gene uncharacterized LOC116658623

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables superoxide-generating NADPH oxidase activator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in phagocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in respiratory burst IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in superoxide anion generation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of NADPH oxidase complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
neutrophil cytosol factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Camelus ferus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BCGSAC_Cfer_1.0 Primary Assembly

Genomic

  1. NC_045716.1 Reference BCGSAC_Cfer_1.0 Primary Assembly

    Range
    1578851..1604285
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_032463560.1XP_032319451.1  neutrophil cytosol factor 2

    UniProtKB/TrEMBL
    A0A8B8RND9
    Related
    ENSCFEP00005017210.1, ENSCFET00005019193.1
    Conserved Domains (7) summary
    cd06406
    Location:351429
    PB1_P67; A PB1 domain is present in p67 proteins which forms a signaling complex with p40, a crucial step for activation of NADPH oxidase during phagocytosis. PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in ...
    cd11871
    Location:244297
    SH3_p67phox_N; N-terminal (or first) Src Homology 3 domain of the p67phox subunit of NADPH oxidase
    cd12046
    Location:461513
    SH3_p67phox_C; C-terminal (or second) Src Homology 3 domain of the p67phox subunit of NADPH oxidase
    COG0457
    Location:6173
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:632
    TPR; TPR repeat [structural motif]
    pfam13424
    Location:42102
    TPR_12; Tetratricopeptide repeat
    pfam00515
    Location:7199
    TPR_1; Tetratricopeptide repeat