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SQSTM1 sequestosome 1 [ Tupaia chinensis (Chinese tree shrew) ]

Gene ID: 102498598, updated on 10-Mar-2024

Summary

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Gene symbol
SQSTM1
Gene description
sequestosome 1
Locus tag
TREES_T100007535
Gene type
protein coding
RefSeq status
MODEL
Organism
Tupaia chinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
7
Annotation release Status Assembly Chr Location
102 current TupChi_1.0 (GCF_000334495.1) Unplaced Scaffold NW_006159689.1 (1371900..1381067, complement)

NW_006159689.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114007658 Neighboring gene MRN complex interacting protein Neighboring gene uncharacterized LOC114007659 Neighboring gene alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006159689 Unplaced Scaffold Reference TupChi_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables K63-linked polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase C binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in aggrephagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endosome organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in aggresome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in amphisome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sequestosome-1
Names
Sequestosome-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tupaia chinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TupChi_1.0

Genomic

  1. NW_006159689.1 Reference TupChi_1.0

    Range
    1371900..1381067 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006147455.2 → XP_006147517.2  sequestosome-1

    UniProtKB/TrEMBL
    L9KW01
    Conserved Domains (3) summary
    cd06402
    Location:4 → 102
    PB1_p62; The PB1 domain is an essential part of p62 scaffold protein (alias sequestosome 1,SQSTM) involved in cell signaling, receptor internalization, and protein turnover. The PB1 domain is a modular domain mediating specific protein-protein interaction which ...
    cd02340
    Location:126 → 168
    ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
    cl21463
    Location:382 → 442
    UBA_like_SF; UBA domain-like superfamily
Nucleotide Protein
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