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AGRN agrin [ Tupaia chinensis (Chinese tree shrew) ]

Gene ID: 102496812, updated on 10-Mar-2024

Summary

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Gene symbol
AGRN
Gene description
agrin
Locus tag
TREES_T100002201
Gene type
protein coding
RefSeq status
MODEL
Organism
Tupaia chinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Scandentia; Tupaiidae; Tupaia
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
39
Annotation release Status Assembly Chr Location
102 current TupChi_1.0 (GCF_000334495.1) Unplaced Scaffold NW_006203430.1 (8851233..8895658)

NW_006203430.1Genomic Context describing neighboring genes Neighboring gene hes family bHLH transcription factor 4 Neighboring gene ISG15 ubiquitin like modifier Neighboring gene tyrosine-protein phosphatase non-receptor type 11-like Neighboring gene ring finger protein 223

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006203430 Unplaced Scaffold Reference TupChi_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus. Yan H, et al. Elife, 2012 Nov 13. PMID 23150796, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables laminin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled acetylcholine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor clustering IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
agrin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Tupaia chinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference TupChi_1.0

Genomic

  1. NW_006203430.1 Reference TupChi_1.0

    Range
    8851233..8895658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014582336.2 → XP_014437822.1  agrin isoform X2

    UniProtKB/TrEMBL
    L8YCF8
    Conserved Domains (9) summary
    smart00280
    Location:492 → 537
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1131 → 1255
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1826 → 1857
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:424 → 464
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    pfam00008
    Location:1335 → 1363
    EGF; EGF-like domain
    pfam00050
    Location:352 → 392
    Kazal_1; Kazal-type serine protease inhibitor domain
    pfam00053
    Location:796 → 838
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1400 → 1531
    Laminin_G_1; Laminin G domain
    pfam03146
    Location:47 → 149
    NtA; Agrin NtA domain

  2. XM_014582335.2 → XP_014437821.1  agrin isoform X1

    UniProtKB/TrEMBL
    L8YCF8
    Conserved Domains (9) summary
    smart00280
    Location:492 → 537
    KAZAL; Kazal type serine protease inhibitors
    smart00200
    Location:1131 → 1255
    SEA; Domain found in sea urchin sperm protein, enterokinase, agrin
    cd00054
    Location:1822 → 1853
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00104
    Location:424 → 464
    KAZAL_FS; Kazal type serine protease inhibitors and follistatin-like domains. Kazal inhibitors inhibit serine proteases, such as, trypsin, chyomotrypsin, avian ovomucoids, and elastases. The inhibitory domain has one reactive site peptide bond, which serves the ...
    pfam00008
    Location:1335 → 1363
    EGF; EGF-like domain
    pfam00050
    Location:352 → 392
    Kazal_1; Kazal-type serine protease inhibitor domain
    pfam00053
    Location:796 → 838
    Laminin_EGF; Laminin EGF domain
    pfam00054
    Location:1400 → 1531
    Laminin_G_1; Laminin G domain
    pfam03146
    Location:47 → 149
    NtA; Agrin NtA domain
Nucleotide Protein
Heading Accession and Version

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