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MIR1277 microRNA mir-1277 [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 102465029, updated on 13-Apr-2024

Summary

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Gene symbol
MIR1277
Gene description
microRNA mir-1277
See related
miRBase:MI0020722
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Also known as
ggo-mir-1277
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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Location:
chromosome: X
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) X NC_073247.2 (130110775..130110882)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) X NC_073247.1 (130102487..130102594)

Chromosome X - NC_073247.2Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene kelch like family member 13 Neighboring gene WD repeat domain 44 Neighboring gene dedicator of cytokinesis 11 Neighboring gene small nucleolar RNA SNORA35 Neighboring gene interleukin 13 receptor subunit alpha 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of primate miRNAs by high throughput sequencing of small RNA libraries. Dannemann M, et al. BMC Genomics, 2012 Mar 27. PMID 22453055, Free PMC Article
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • microRNA 1277

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_106388.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    JARGGP020000024

RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_073247.2 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    130110775..130110882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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