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    SLC17A2 solute carrier family 17 (sodium phosphate), member 2 [ Homo sapiens ]

    Gene ID: 10246, updated on 11-May-2012
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    Summary

    Official Symbol
    SLC17A2provided by HGNC
    Official Full Name
    solute carrier family 17 (sodium phosphate), member 2provided by HGNC
    Primary source
    HGNC:10930
    See related
    Ensembl:ENSG00000112337; HPRD:10232; MIM:611049; Vega:OTTHUMG00000014413
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NPT3; MGC138238
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    Genomic context

    Location :
    6p21.3
    Sequence :
    Chromosome: 6; NC_000006.11 (25912982..25930946, complement)
    See SLC17A2 in Epigenomics, MapViewer

    Chromosome 6 - NC_000006.11Genomic Context describing neighboring genes Neighboring gene solute carrier family 17 (sodium phosphate), member 3 Neighboring gene histone cluster 1, H2a, pseudogene 2 Neighboring gene tripartite motif containing 38 Neighboring gene histone cluster 1, H1, pseudogene 2

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease. Stark K, et al. PLoS One, 2009 Nov 5. PMID 19890391.
    2. TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. Vanderwerf SM, et al. Blood, 2009 Dec 17. PMID 19850743.
    3. The DNA sequence and analysis of human chromosome 6. Mungall AJ, et al. Nature, 2003 Oct 23. PMID 14574404.
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
    5. A 1.1-Mb transcript map of the hereditary hemochromatosis locus. Ruddy DA, et al. Genome Res, 1997 May. PMID 9149941.

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. Observational study of gene-disease association. (HuGE Navigator)
      Title: Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease.
    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:115540 BioGRID:113164 UBC    BioGRID  PubMed Reconstituted Complex 
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    General gene information

    Markers

    Genotypes

    Homology

    Pathways from BioSystems

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    sodium:phosphate symporter activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    phosphate-containing compound metabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    integral to plasma membrane TAS
    Traceable Author Statement
    more info
    		 PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    membrane fraction TAS
    Traceable Author Statement
    more info
    		 PubMed 
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    General protein information

    Preferred Names
    sodium-dependent phosphate transport protein 3
    Names
    sodium-dependent phosphate transport protein 3
    Na(+)/PI cotransporter 3
    sodium phosphate transporter 3
    sodium/phosphate cotransporter 3
    solute carrier family 17 member 2
    solute carrier family 17 (vesicular glutamate transporter), member 2
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_005835.2 → NP_005826.1  sodium-dependent phosphate transport protein 3

      Status: VALIDATED

      Source sequence(s)
      AL138726, BJ993843, U90544
      Consensus CDS
      CCDS4567.1
      UniProtKB/Swiss-Prot
      O00624
      Related
      ENSP00000353677, OTTHUMP00000016129, ENST00000360488, OTTHUMT00000040074
      Conserved Domains (1) summary
      cd06174
      Location:81 – 342
      Blast Score: 246
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000006.11 Reference GRCh37.p5 Primary Assembly

      Range
      25912982..25930946, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000138.1 Alternate HuRef

      Range
      25856022..25873987, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AL138726.12 CAC69101.1
      CAI19542.1
    genomic CH471087.1 EAW55498.1
      EAW55499.1
      EAW55500.1
    genomic U91328.1 AAB82085.1
    mRNA BC104822.1 AAI04823.1
    mRNA BC112033.1 AAI12034.1
    mRNA BC143317.1 None
    mRNA BC143323.1 None
    mRNA BJ993843.1 None
    mRNA U90544.1 AAB53422.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    O00624.2 GenPept UniProtKB/Swiss-Prot:O00624
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
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      Supplemental Content

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