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MUSK muscle associated receptor tyrosine kinase [ Pelodiscus sinensis (Chinese soft-shelled turtle) ]

Gene ID: 102446033, updated on 11-Apr-2024

Summary

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Gene symbol
MUSK
Gene description
muscle associated receptor tyrosine kinase
See related
Ensembl:ENSPSIG00000011443
Gene type
protein coding
RefSeq status
MODEL
Organism
Pelodiscus sinensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Trionychia; Trionychidae; Pelodiscus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
102 current PelSin_1.0 (GCF_000230535.1) Unplaced Scaffold NW_005853731.1 (683996..760001, complement)

NW_005853731.1Genomic Context describing neighboring genes Neighboring gene atrial natriuretic peptide receptor 1-like Neighboring gene lysophosphatidic acid receptor 1 Neighboring gene uncharacterized LOC112544942 Neighboring gene uncharacterized LOC102446578

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005853731 Unplaced Scaffold Reference PelSin_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables axon guidance receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synapse organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
muscle, skeletal receptor tyrosine-protein kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pelodiscus sinensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PelSin_1.0 Primary Assembly

Genomic

  1. NW_005853731.1 Reference PelSin_1.0 Primary Assembly

    Range
    683996..760001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014570937.2 → XP_014426423.1  muscle, skeletal receptor tyrosine-protein kinase isoform X3

    UniProtKB/TrEMBL
    K7FXV7
    Conserved Domains (8) summary
    cd05050
    Location:621 → 910
    PTKc_Musk; Catalytic domain of the Protein Tyrosine Kinase, Muscle-specific kinase
    cd00096
    Location:250 → 317
    Ig; Immunoglobulin domain
    smart00130
    Location:437 → 518
    KR; Kringle domain
    smart00410
    Location:148 → 222
    IG_like; Immunoglobulin like
    pfam07679
    Location:234 → 324
    I-set; Immunoglobulin I-set domain
    pfam07714
    Location:627 → 908
    Pkinase_Tyr; Protein tyrosine kinase
    cl02447
    Location:334 → 430
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain
    cl11960
    Location:156 → 222
    Ig; Immunoglobulin domain

  2. XM_014570936.2 → XP_014426422.1  muscle, skeletal receptor tyrosine-protein kinase isoform X2

    UniProtKB/TrEMBL
    K7FXV7
    Conserved Domains (8) summary
    cd05050
    Location:661 → 950
    PTKc_Musk; Catalytic domain of the Protein Tyrosine Kinase, Muscle-specific kinase
    cd00096
    Location:250 → 317
    Ig; Immunoglobulin domain
    cd07469
    Location:334 → 475
    CRD_TK_ROR_related; Cysteine-rich domain of proteins similar to tyrosine kinase-like orphan receptors
    smart00130
    Location:477 → 558
    KR; Kringle domain
    smart00410
    Location:148 → 222
    IG_like; Immunoglobulin like
    pfam07679
    Location:234 → 324
    I-set; Immunoglobulin I-set domain
    pfam07714
    Location:667 → 948
    Pkinase_Tyr; Protein tyrosine kinase
    cl11960
    Location:156 → 222
    Ig; Immunoglobulin domain

  3. XM_006117991.3 → XP_006118053.1  muscle, skeletal receptor tyrosine-protein kinase isoform X1

    UniProtKB/TrEMBL
    K7FXV7
    Related
    ENSPSIP00000012880.1, ENSPSIT00000012942.1
    Conserved Domains (8) summary
    cd05050
    Location:669 → 958
    PTKc_Musk; Catalytic domain of the Protein Tyrosine Kinase, Muscle-specific kinase
    cd00096
    Location:250 → 317
    Ig; Immunoglobulin domain
    cd07469
    Location:334 → 478
    CRD_TK_ROR_related; Cysteine-rich domain of proteins similar to tyrosine kinase-like orphan receptors
    smart00130
    Location:485 → 566
    KR; Kringle domain
    smart00410
    Location:148 → 222
    IG_like; Immunoglobulin like
    pfam07679
    Location:234 → 324
    I-set; Immunoglobulin I-set domain
    pfam07714
    Location:675 → 956
    Pkinase_Tyr; Protein tyrosine kinase
    cl11960
    Location:156 → 222
    Ig; Immunoglobulin domain

  4. XM_014570938.2 → XP_014426424.1  muscle, skeletal receptor tyrosine-protein kinase isoform X4

    UniProtKB/TrEMBL
    K7FXX0
    Conserved Domains (7) summary
    cd05050
    Location:504 → 793
    PTKc_Musk; Catalytic domain of the Protein Tyrosine Kinase, Muscle-specific kinase
    cd00096
    Location:85 → 152
    Ig; Immunoglobulin domain
    cd07469
    Location:169 → 313
    CRD_TK_ROR_related; Cysteine-rich domain of proteins similar to tyrosine kinase-like orphan receptors
    smart00130
    Location:320 → 401
    KR; Kringle domain
    pfam07679
    Location:69 → 159
    I-set; Immunoglobulin I-set domain
    pfam07714
    Location:510 → 791
    Pkinase_Tyr; Protein tyrosine kinase
    cl11960
    Location:2 → 57
    Ig; Immunoglobulin domain

  5. XM_025182080.1 → XP_025037865.1  muscle, skeletal receptor tyrosine-protein kinase isoform X5

    Conserved Domains (6) summary
    cd07469
    Location:334 → 478
    CRD_TK_ROR_related; Cysteine-rich domain of proteins similar to tyrosine kinase-like orphan receptors
    smart00130
    Location:485 → 566
    KR; Kringle domain
    pfam07679
    Location:142 → 220
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:234 → 307
    Ig_3; Immunoglobulin domain
    cl11960
    Location:70 → 127
    Ig; Immunoglobulin domain
    cl21453
    Location:669 → 742
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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