Format

Send to:

Choose Destination

Lars2 leucyl-tRNA synthetase, mitochondrial [ Mus musculus (house mouse) ]

Gene ID: 102436, updated on 8-May-2016
Official Symbol
Lars2provided by MGI
Official Full Name
leucyl-tRNA synthetase, mitochondrialprovided by MGI
Primary source
MGI:MGI:2142973
See related
Ensembl:ENSMUSG00000035202
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
LEURS; AI035546; Kiaa0028
Orthologs
Location:
9 73.92 cM; 9 F
Exon count:
22
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (123366940..123462666)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (123276058..123371782)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 39466 Neighboring gene sterol carrier protein 2, pseudogene 2 Neighboring gene predicted gene, 40586 Neighboring gene LIM domains containing 1

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
aminoacyl-tRNA editing activity IEA
Inferred from Electronic Annotation
more info
 
aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
leucine-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
leucine-tRNA ligase activity ISO
Inferred from Sequence Orthology
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
leucyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
 
leucyl-tRNA aminoacylation ISO
Inferred from Sequence Orthology
more info
 
tRNA aminoacylation for protein translation IEA
Inferred from Electronic Annotation
more info
 
translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
probable leucine--tRNA ligase, mitochondrial
Names
leucine--tRNA ligase
probable leucyl-tRNA synthetase, mitochondrial
NP_694808.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153168.2NP_694808.1  probable leucine--tRNA ligase, mitochondrial

    See identical proteins and their annotated locations for NP_694808.1

    Status: PROVISIONAL

    Source sequence(s)
    AC125254, AC164123
    Consensus CDS
    CCDS23659.1
    UniProtKB/Swiss-Prot
    Q8VDC0
    Related
    ENSMUSP00000036710, ENSMUST00000038863
    Conserved Domains (4) summary
    cd07958
    Location:677802
    Anticodon_Ia_Leu_BEm; Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases
    cd00812
    Location:82677
    LeuRS_core; catalytic core domain of leucyl-tRNA synthetases
    PRK00390
    Location:56900
    leuS; leucyl-tRNA synthetase; Validated
    pfam13603
    Location:269429
    tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    123366940..123462666
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511907.2XP_006511970.1  

    Conserved Domains (3) summary
    cd07958
    Location:429554
    Anticodon_Ia_Leu_BEm; Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases
    pfam13603
    Location:21181
    tRNA-synt_1_2; Leucyl-tRNA synthetase, Domain 2
    cl00015
    Location:195429
    nt_trans; nucleotidyl transferase superfamily

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    123819514..123915073
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)