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CHN1 chimerin 1 [ Bubalus bubalis (water buffalo) ]

Gene ID: 102410031, updated on 10-Mar-2024

Summary

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Gene symbol
CHN1
Gene description
chimerin 1
See related
EnsemblRapid:ENSBALG00030025506
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 2 NC_059158.1 (73984187..74186237)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 2 NC_058344.1 (73399913..73602654)

Chromosome 2 - NC_059158.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123330926 Neighboring gene ATP synthase membrane subunit c locus 3 Neighboring gene activating transcription factor 2 Neighboring gene uncharacterized LOC123330924 Neighboring gene small nucleolar RNA SNORA57 Neighboring gene uncharacterized LOC112581736 Neighboring gene cholinergic receptor nicotinic alpha 1 subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De Novo Transcriptome Assembly of the Chinese Swamp Buffalo by RNA Sequencing and SSR Marker Discovery. Deng T, et al. PLoS One, 2016. PMID 26766209, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ephrin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ephrin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of small GTPase mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
N-chimaerin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059158.1 Reference NDDB_SH_1 Primary Assembly

    Range
    73984187..74186237
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044933506.2 → XP_044789441.1  N-chimaerin isoform X1

    Related
    ENSBALP00030048472.1, ENSBALT00030071950.1

  2. XM_044933518.2 → XP_044789453.1  N-chimaerin isoform X5

  3. XM_006073585.4 → XP_006073647.1  N-chimaerin isoform X2

    See identical proteins and their annotated locations for XP_006073647.1

    Related
    ENSBALP00030048429.1, ENSBALT00030071886.1
    Conserved Domains (3) summary
    cd10352
    Location:42 → 128
    SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
    cd04372
    Location:266 → 459
    RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
    cd20856
    Location:201 → 257
    C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins

  4. XM_025274592.3 → XP_025130377.1  N-chimaerin isoform X6

    Related
    ENSBALP00030048377.1, ENSBALT00030071808.1
    Conserved Domains (2) summary
    cd04372
    Location:121 → 314
    RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
    pfam00130
    Location:61 → 113
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  5. XM_044933512.2 → XP_044789447.1  N-chimaerin isoform X4

    Related
    ENSBALP00030048397.1, ENSBALT00030071837.1
    Conserved Domains (3) summary
    cd10352
    Location:20 → 106
    SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
    cd04372
    Location:244 → 437
    RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
    cd20856
    Location:179 → 235
    C1_alphaCHN; protein kinase C conserved region 1 (C1 domain) found in alpha-chimaerin and similar proteins

  6. XM_025274568.3 → XP_025130353.1  N-chimaerin isoform X3

    Related
    ENSBALP00030048325.1, ENSBALT00030071731.1
    Conserved Domains (3) summary
    cd10352
    Location:36 → 122
    SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
    cd04372
    Location:260 → 453
    RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
    pfam00130
    Location:200 → 252
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  7. XM_025274598.3 → XP_025130383.1  N-chimaerin isoform X7

    Related
    ENSBALP00030048251.1, ENSBALT00030071620.1
    Conserved Domains (2) summary
    cd04372
    Location:86 → 279
    RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
    cl00040
    Location:22 → 80
    C1; protein kinase C conserved region 1 (C1 domain) superfamily
Nucleotide Protein
Heading Accession and Version

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