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APLP1 amyloid beta precursor like protein 1 [ Bubalus bubalis (water buffalo) ]

Gene ID: 102407479, updated on 10-Mar-2024

Summary

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Gene symbol
APLP1
Gene description
amyloid beta precursor like protein 1
See related
EnsemblRapid:ENSBALG00030020852
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 18
Exon count:
17
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 18 NC_059174.1 (46210926..46220705)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 18 NC_058360.1 (46202465..46212244)

Chromosome 18 - NC_059174.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene NPHS1 adhesion molecule, nephrin Neighboring gene kirre like nephrin family adhesion molecule 2 Neighboring gene NFKB inhibitor delta Neighboring gene hematopoietic cell signal transducer Neighboring gene transmembrane immune signaling adaptor TYROBP

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha-2A adrenergic receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables alpha-2B adrenergic receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables alpha-2C adrenergic receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transition metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
amyloid-like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059174.1 Reference NDDB_SH_1 Primary Assembly

    Range
    46210926..46220705
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006068777.4 → XP_006068839.1  amyloid-like protein 1 isoform X1

    Related
    ENSBALP00030039440.1, ENSBALT00030058665.1
    Conserved Domains (5) summary
    smart00006
    Location:40 → 205
    A4_EXTRA; amyloid A4
    pfam02177
    Location:49 → 148
    APP_N; Amyloid A4 N-terminal heparin-binding
    pfam10515
    Location:600 → 643
    APP_amyloid; beta-amyloid precursor protein C-terminus
    pfam12924
    Location:150 → 205
    APP_Cu_bd; Copper-binding of amyloid precursor, CuBD
    pfam12925
    Location:280 → 462
    APP_E2; E2 domain of amyloid precursor protein

  2. XM_006068778.4 → XP_006068840.1  amyloid-like protein 1 isoform X2

    Related
    ENSBALP00030039553.1, ENSBALT00030058820.1
    Conserved Domains (5) summary
    smart00006
    Location:40 → 205
    A4_EXTRA; amyloid A4
    pfam02177
    Location:49 → 148
    APP_N; Amyloid A4 N-terminal heparin-binding
    pfam10515
    Location:599 → 642
    APP_amyloid; beta-amyloid precursor protein C-terminus
    pfam12924
    Location:150 → 205
    APP_Cu_bd; Copper-binding of amyloid precursor, CuBD
    pfam12925
    Location:280 → 462
    APP_E2; E2 domain of amyloid precursor protein
Nucleotide Protein
Heading Accession and Version

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