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DUSP2 dual specificity phosphatase 2 [ Bubalus bubalis (water buffalo) ]

Gene ID: 102399462, updated on 10-Mar-2024

Summary

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Gene symbol
DUSP2
Gene description
dual specificity phosphatase 2
See related
EnsemblRapid:ENSBALG00030018227
Gene type
protein coding
RefSeq status
MODEL
Organism
Bubalus bubalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bubalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
4
Annotation release Status Assembly Chr Location
103 current NDDB_SH_1 (GCF_019923935.1) 12 NC_059168.1 (2204143..2206823, complement)
102 previous assembly NDDB_DH_1 (GCF_019923925.1) 12 NC_058354.1 (2210052..2212732, complement)

Chromosome 12 - NC_059168.1Genomic Context describing neighboring genes Neighboring gene adrenoceptor alpha 2B Neighboring gene astacin like metalloendopeptidase Neighboring gene StAR related lipid transfer domain containing 7 Neighboring gene transmembrane protein 127

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MAP kinase tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoderm formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity protein phosphatase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bubalus bubalis Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NDDB_SH_1 Primary Assembly

Genomic

  1. NC_059168.1 Reference NDDB_SH_1 Primary Assembly

    Range
    2204143..2206823 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025260615.2 → XP_025116400.1  dual specificity protein phosphatase 2

    Related
    ENSBALP00030034342.1, ENSBALT00030051087.1
    Conserved Domains (2) summary
    cd00127
    Location:172 → 308
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
    cd01446
    Location:8 → 143
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...
Nucleotide Protein
Heading Accession and Version

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