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UBA3 ubiquitin-like modifier activating enzyme 3 [ Latimeria chalumnae (coelacanth) ]

Gene ID: 102351153, updated on 10-Mar-2024

Summary

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Gene symbol
UBA3
Gene description
ubiquitin-like modifier activating enzyme 3
See related
Ensembl:ENSLACG00000014006
Gene type
protein coding
RefSeq status
MODEL
Organism
Latimeria chalumnae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Coelacanthiformes; Coelacanthidae; Latimeria
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
101 current LatCha1 (GCF_000225785.1) Unplaced Scaffold NW_005819256.1 (945312..976157)

NW_005819256.1Genomic Context describing neighboring genes Neighboring gene leiomodin 3 (fetal) Neighboring gene ADP ribosylation factor like GTPase 6 interacting protein 5 Neighboring gene TATA element modulatory factor 1 Neighboring gene EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005819256.1 Unplaced Scaffold Reference LatCha1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NEDD8 activating enzyme activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein neddylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NEDD8-activating enzyme E1 catalytic subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Latimeria chalumnae Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LatCha1 Primary Assembly

Genomic

  1. NW_005819256.1 Reference LatCha1 Primary Assembly

    Range
    945312..976157
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005995221.2 → XP_005995283.1  NEDD8-activating enzyme E1 catalytic subunit isoform X1

    UniProtKB/TrEMBL
    H3B1Y6
    Related
    ENSLACP00000015907.2, ENSLACT00000016017.2
    Conserved Domains (3) summary
    cd01488
    Location:70 → 367
    Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
    pfam00899
    Location:66 → 365
    ThiF; ThiF family
    pfam08825
    Location:375 → 460
    E2_bind; E2 binding domain

  2. XM_005995224.2 → XP_005995286.1  NEDD8-activating enzyme E1 catalytic subunit isoform X4

    Conserved Domains (3) summary
    cd01488
    Location:70 → 341
    Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
    pfam00899
    Location:66 → 339
    ThiF; ThiF family
    pfam08825
    Location:349 → 434
    E2_bind; E2 binding domain

  3. XM_014487975.1 → XP_014343461.1  NEDD8-activating enzyme E1 catalytic subunit isoform X6

  4. XM_014487973.1 → XP_014343459.1  NEDD8-activating enzyme E1 catalytic subunit isoform X5

  5. XM_005995225.2 → XP_005995287.1  NEDD8-activating enzyme E1 catalytic subunit isoform X7

    Conserved Domains (3) summary
    pfam00899
    Location:66 → 287
    ThiF; ThiF family
    pfam08825
    Location:297 → 382
    E2_bind; E2 binding domain
    cl22428
    Location:70 → 289
    E1_enzyme_family; Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common ...

  6. XM_005995222.2 → XP_005995284.1  NEDD8-activating enzyme E1 catalytic subunit isoform X2

    Conserved Domains (3) summary
    cd01488
    Location:57 → 354
    Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
    pfam00899
    Location:53 → 352
    ThiF; ThiF family
    pfam08825
    Location:362 → 447
    E2_bind; E2 binding domain

  7. XM_005995223.2 → XP_005995285.1  NEDD8-activating enzyme E1 catalytic subunit isoform X3

    Conserved Domains (3) summary
    cd01488
    Location:50 → 347
    Uba3_RUB; Ubiquitin activating enzyme (E1) subunit UBA3. UBA3 is part of the heterodimeric activating enzyme (E1), specific for the Rub family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to ...
    pfam00899
    Location:46 → 345
    ThiF; ThiF family
    pfam08825
    Location:355 → 440
    E2_bind; E2 binding domain
Nucleotide Protein
Heading Accession and Version

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