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PMS1 PMS1 homolog 1, mismatch repair system component [ Latimeria chalumnae (coelacanth) ]

Gene ID: 102349367, updated on 10-Mar-2024

Summary

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Gene symbol
PMS1
Gene description
PMS1 homolog 1, mismatch repair system component
See related
Ensembl:ENSLACG00000014506
Gene type
protein coding
RefSeq status
MODEL
Organism
Latimeria chalumnae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Coelacanthiformes; Coelacanthidae; Latimeria
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
101 current LatCha1 (GCF_000225785.1) Unplaced Scaffold NW_005819327.1 (1041421..1100928)

NW_005819327.1Genomic Context describing neighboring genes Neighboring gene adenosine deaminase tRNA specific 3 Neighboring gene ORMDL sphingolipid biosynthesis regulator 1 Neighboring gene SAP domain-containing ribonucleoprotein-like Neighboring gene uncharacterized LOC102350444 Neighboring gene myostatin b

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005819327.1 Unplaced Scaffold Reference LatCha1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP-dependent DNA damage sensor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables mismatched DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mismatch repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MutLalpha complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
PMS1 protein homolog 1
Names
PMS1 postmeiotic segregation increased 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Latimeria chalumnae Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LatCha1 Primary Assembly

Genomic

  1. NW_005819327.1 Reference LatCha1 Primary Assembly

    Range
    1041421..1100928
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005996535.2 → XP_005996597.1  PMS1 protein homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_005996597.1

    UniProtKB/TrEMBL
    H3B3J2, H3B3J3
    Conserved Domains (4) summary
    cd01390
    Location:577 → 639
    HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    cd03485
    Location:205 → 339
    MutL_Trans_hPMS_1_like; MutL_Trans_hPMS1_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM1 (hPSM1) and yeast MLH2. hPSM1 and yMLH2 are members of the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is ...
    TIGR00585
    Location:1 → 319
    mutl; DNA mismatch repair protein MutL
    cl00075
    Location:20 → 124
    HATPase_c; Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins

  2. XM_005996537.2 → XP_005996599.1  PMS1 protein homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_005996599.1

    UniProtKB/TrEMBL
    H3B3J2, H3B3J3
    Related
    ENSLACP00000016464.1, ENSLACT00000016578.1
    Conserved Domains (4) summary
    cd01390
    Location:577 → 639
    HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    cd03485
    Location:205 → 339
    MutL_Trans_hPMS_1_like; MutL_Trans_hPMS1_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM1 (hPSM1) and yeast MLH2. hPSM1 and yMLH2 are members of the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is ...
    TIGR00585
    Location:1 → 319
    mutl; DNA mismatch repair protein MutL
    cl00075
    Location:20 → 124
    HATPase_c; Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins

  3. XM_014488673.1 → XP_014344159.1  PMS1 protein homolog 1 isoform X1

    UniProtKB/TrEMBL
    H3B3J2, H3B3J3
    Conserved Domains (4) summary
    cd01390
    Location:577 → 639
    HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    cd03485
    Location:205 → 339
    MutL_Trans_hPMS_1_like; MutL_Trans_hPMS1_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM1 (hPSM1) and yeast MLH2. hPSM1 and yMLH2 are members of the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is ...
    TIGR00585
    Location:1 → 319
    mutl; DNA mismatch repair protein MutL
    cl00075
    Location:20 → 124
    HATPase_c; Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins

  4. XM_005996536.1 → XP_005996598.1  PMS1 protein homolog 1 isoform X1

    See identical proteins and their annotated locations for XP_005996598.1

    UniProtKB/TrEMBL
    H3B3J2, H3B3J3
    Related
    ENSLACP00000016463.1, ENSLACT00000016577.1
    Conserved Domains (4) summary
    cd01390
    Location:577 → 639
    HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    cd03485
    Location:205 → 339
    MutL_Trans_hPMS_1_like; MutL_Trans_hPMS1_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM1 (hPSM1) and yeast MLH2. hPSM1 and yMLH2 are members of the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is ...
    TIGR00585
    Location:1 → 319
    mutl; DNA mismatch repair protein MutL
    cl00075
    Location:20 → 124
    HATPase_c; Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins

  5. XM_005996538.2 → XP_005996600.1  PMS1 protein homolog 1 isoform X2

    Conserved Domains (2) summary
    cd01390
    Location:391 → 453
    HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
    cd03485
    Location:19 → 153
    MutL_Trans_hPMS_1_like; MutL_Trans_hPMS1_like: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to human PSM1 (hPSM1) and yeast MLH2. hPSM1 and yMLH2 are members of the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is ...
Nucleotide Protein
Heading Accession and Version

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