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alox12 arachidonate 12-lipoxygenase [ Haplochromis burtoni (Burton's mouthbrooder) ]

Gene ID: 102289271, updated on 10-Mar-2024

Summary

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Gene symbol
alox12
Gene description
arachidonate 12-lipoxygenase
See related
Ensembl:ENSHBUG00000014640
Gene type
protein coding
RefSeq status
MODEL
Organism
Haplochromis burtoni
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Haplochromis
Also known as
alox15
Orthologs
zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current NCSU_Asbu1 (GCF_018398535.1) Unplaced Scaffold NW_024582799.1 (451812..465507, complement)
101 previous assembly AstBur1.0 (GCF_000239415.1) Unplaced Scaffold NW_005179853.1 (29700..43241)

NW_024582799.1Genomic Context describing neighboring genes Neighboring gene chromatin complexes subunit BAP18 Neighboring gene ribonuclease kappa-A Neighboring gene proline, glutamate and leucine rich protein 1 Neighboring gene mediator complex subunit 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables arachidonate 15-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 12-lipoxygenase, 12S-type
Names
arachidonate 15-lipoxygenase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Haplochromis burtoni Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NCSU_Asbu1 Primary Assembly

Genomic

  1. NW_024582799.1 Reference NCSU_Asbu1 Primary Assembly

    Range
    451812..465507 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042213367.1 → XP_042069301.1  arachidonate 12-lipoxygenase, 12S-type

    UniProtKB/TrEMBL
    A0A3Q3CSW1
    Conserved Domains (2) summary
    cd01753
    Location:3 → 115
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
    pfam00305
    Location:227 → 649
    Lipoxygenase
Nucleotide Protein
Heading Accession and Version

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