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SPTBN2 spectrin beta, non-erythrocytic 2 [ Bos mutus (wild yak) ]

Gene ID: 102269667, updated on 10-Mar-2024

Summary

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Gene symbol
SPTBN2
Gene description
spectrin beta, non-erythrocytic 2
Locus tag
M91_14015
See related
Ensembl:ENSBMUG00000021027
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos mutus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See SPTBN2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
36
Annotation release Status Assembly Chr Location
101 current BosGru_v2.0 (GCF_000298355.1) Unplaced Scaffold NW_005394695.1 (381668..415773, complement)

NW_005394695.1Genomic Context describing neighboring genes Neighboring gene RNA-binding protein 4 Neighboring gene RNA binding motif protein 4B Neighboring gene TOP6B like initiator of meiotic double strand breaks Neighboring gene Ras converting CAAX endopeptidase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005394695.1 Unplaced Scaffold Reference BosGru_v2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of spectrin IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
spectrin beta chain, non-erythrocytic 2
Names
Spectrin beta chain, brain 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos mutus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BosGru_v2.0 Primary Assembly

Genomic

  1. NW_005394695.1 Reference BosGru_v2.0 Primary Assembly

    Range
    381668..415773 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005903576.2 → XP_005903638.1  spectrin beta chain, non-erythrocytic 2

    UniProtKB/TrEMBL
    L8I3C5
    Related
    ENSBMUP00000028094.1, ENSBMUT00000032368.1
    Conserved Domains (7) summary
    smart00150
    Location:1841 → 1898
    SPEC; Spectrin repeats
    smart00033
    Location:61 → 159
    CH; Calponin homology domain
    cd00014
    Location:177 → 280
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1207 → 1411
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd10571
    Location:2042 → 2145
    PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
    pfam00169
    Location:2042 → 2145
    PH; PH domain
    pfam00435
    Location:429 → 522
    Spectrin; Spectrin repeat
Nucleotide Protein
Heading Accession and Version

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