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MELK maternal embryonic leucine zipper kinase [ Myotis brandtii (Brandt's bat) ]

Gene ID: 102257383, updated on 30-Mar-2024

Summary

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Gene symbol
MELK
Gene description
maternal embryonic leucine zipper kinase
Locus tag
D623_10017836
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis brandtii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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See MELK in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
101 current ASM41265v1 (GCF_000412655.1) Unplaced Scaffold NW_005371249.1 (1260313..1319765, complement)

NW_005371249.1Genomic Context describing neighboring genes Neighboring gene paired box 5 Neighboring gene sal-like protein 4 Neighboring gene ring finger protein 38 Neighboring gene zinc finger protein 42 homolog Neighboring gene glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005371249.1 Unplaced Scaffold Reference ASM41265v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tau-protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
maternal embryonic leucine zipper kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis brandtii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM41265v1

Genomic

  1. NW_005371249.1 Reference ASM41265v1

    Range
    1260313..1319765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014531547.1 → XP_014387033.1  maternal embryonic leucine zipper kinase isoform X1

    UniProtKB/TrEMBL
    S7NM75
    Conserved Domains (4) summary
    cd12198
    Location:555 → 649
    MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
    smart00220
    Location:11 → 263
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14341
    Location:281 → 332
    UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
    cd14078
    Location:7 → 263
    STKc_MELK; Catalytic domain of the Serine/Threonine Kinase, Maternal Embryonic Leucine zipper Kinase

  2. XM_014531548.1 → XP_014387034.1  maternal embryonic leucine zipper kinase isoform X1

    UniProtKB/TrEMBL
    S7NM75
    Conserved Domains (4) summary
    cd12198
    Location:555 → 649
    MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
    smart00220
    Location:11 → 263
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14341
    Location:281 → 332
    UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
    cd14078
    Location:7 → 263
    STKc_MELK; Catalytic domain of the Serine/Threonine Kinase, Maternal Embryonic Leucine zipper Kinase

  3. XM_014531549.1 → XP_014387035.1  maternal embryonic leucine zipper kinase isoform X2

    UniProtKB/TrEMBL
    S7NM75
    Conserved Domains (4) summary
    cd12198
    Location:520 → 614
    MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
    COG0515
    Location:2 → 329
    SPS1; Serine/threonine protein kinase [Signal transduction mechanisms]
    cd14341
    Location:246 → 297
    UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
    cl21453
    Location:1 → 228
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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