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NSD2 nuclear receptor binding SET domain protein 2 [ Myotis brandtii (Brandt's bat) ]

Gene ID: 102253280, updated on 30-Mar-2024

Summary

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Gene symbol
NSD2
Gene description
nuclear receptor binding SET domain protein 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis brandtii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Also known as
WHSC1
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
101 current ASM41265v1 (GCF_000412655.1) Unplaced Scaffold NW_005372102.1 (2299819..2363478, complement)

NW_005372102.1Genomic Context describing neighboring genes Neighboring gene N-acetyltransferase 8 like Neighboring gene negative elongation factor complex member A Neighboring gene LETM1 and EF-hand domain-containing protein 1, mitochondrial-like Neighboring gene LETM1 and EF-hand domain-containing protein 1, mitochondrial Neighboring gene fibroblast growth factor receptor 3 Neighboring gene transforming acidic coiled-coil containing protein 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005372102.1 Unplaced Scaffold Reference ASM41265v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K36 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase NSD2
Names
Wolf-Hirschhorn syndrome candidate 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis brandtii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM41265v1

Genomic

  1. NW_005372102.1 Reference ASM41265v1

    Range
    2299819..2363478 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014533459.1 → XP_014388945.1  histone-lysine N-methyltransferase NSD2

    Conserved Domains (7) summary
    cd05837
    Location:220 → 328
    MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
    cd05838
    Location:689 → 783
    WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
    smart00570
    Location:823 → 873
    AWS; associated with SET domains
    smart00317
    Location:901 → 1003
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00084
    Location:383 → 432
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd15660
    Location:1058 → 1100
    PHD5_NSD2; PHD finger 5 found in nuclear SET domain-containing protein 2 (NSD2)
    cl22851
    Location:651 → 684
    PHD_SF; PHD finger superfamily
Nucleotide Protein
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