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GEN1 GEN1 Holliday junction 5' flap endonuclease [ Myotis brandtii (Brandt's bat) ]

Gene ID: 102251694, updated on 30-Mar-2024

Summary

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Gene symbol
GEN1
Gene description
GEN1 Holliday junction 5' flap endonuclease
Locus tag
D623_10020187
Gene type
protein coding
RefSeq status
MODEL
Organism
Myotis brandtii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Vespertilionidae; Myotis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
101 current ASM41265v1 (GCF_000412655.1) Unplaced Scaffold NW_005371287.1 (2889697..2948233)

NW_005371287.1Genomic Context describing neighboring genes Neighboring gene visinin like 1 Neighboring gene structural maintenance of chromosomes 6 Neighboring gene mesogenin 1 Neighboring gene potassium voltage-gated channel modifier subfamily S member 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005371287.1 Unplaced Scaffold Reference ASM41265v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii. Seim I, et al. Nat Commun, 2013. PMID 23962925, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-flap endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables four-way junction DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
flap endonuclease GEN homolog 1
Names
Flap endonuclease GEN like protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Myotis brandtii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM41265v1

Genomic

  1. NW_005371287.1 Reference ASM41265v1

    Range
    2889697..2948233
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014531597.1 → XP_014387083.1  flap endonuclease GEN homolog 1 isoform X1

    Conserved Domains (2) summary
    cd09869
    Location:1 → 193
    PIN_GEN1; PIN domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
    cl22433
    Location:195 → 339
    H3TH_StructSpec-5'-nucleases; H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination

  2. XM_014531600.1 → XP_014387086.1  flap endonuclease GEN homolog 1 isoform X4

    Conserved Domains (2) summary
    cd09869
    Location:1 → 193
    PIN_GEN1; PIN domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
    cl22433
    Location:195 → 339
    H3TH_StructSpec-5'-nucleases; H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination

  3. XM_014531598.1 → XP_014387084.1  flap endonuclease GEN homolog 1 isoform X2

    Conserved Domains (2) summary
    cd09869
    Location:1 → 193
    PIN_GEN1; PIN domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
    cl22433
    Location:195 → 339
    H3TH_StructSpec-5'-nucleases; H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination

  4. XM_014531599.1 → XP_014387085.1  flap endonuclease GEN homolog 1 isoform X3

    Conserved Domains (2) summary
    cd09869
    Location:1 → 193
    PIN_GEN1; PIN domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
    cl22433
    Location:195 → 339
    H3TH_StructSpec-5'-nucleases; H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination

  5. XM_005884080.2 → XP_005884142.1  flap endonuclease GEN homolog 1 isoform X5

    See identical proteins and their annotated locations for XP_005884142.1

    UniProtKB/TrEMBL
    S7NMU0
    Conserved Domains (2) summary
    cd09869
    Location:1 → 193
    PIN_GEN1; PIN domain of Gap Endonuclease 1, a structure-specific, divalent-metal-ion dependent, 5' nuclease and homologs
    cl22433
    Location:195 → 339
    H3TH_StructSpec-5'-nucleases; H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination

RNA

  1. XR_001360163.1 RNA Sequence

  2. XR_001360162.1 RNA Sequence

  3. XR_001360164.1 RNA Sequence

  4. XR_001360165.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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