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iqgap1 IQ motif containing GTPase activating protein 1 [ Pundamilia nyererei ]

Gene ID: 102212947, updated on 10-Mar-2024

Summary

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Gene symbol
iqgap1
Gene description
IQ motif containing GTPase activating protein 1
See related
Ensembl:ENSPNYG00000002755
Gene type
protein coding
RefSeq status
MODEL
Organism
Pundamilia nyererei
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Pundamilia
Orthologs
human zebrafish all
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Genomic context

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See iqgap1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
37
Annotation release Status Assembly Chr Location
101 current PunNye1.0 (GCF_000239375.1) Unplaced Scaffold NW_005187582.1 (636431..679241)

NW_005187582.1Genomic Context describing neighboring genes Neighboring gene cocaine- and amphetamine-regulated transcript 3 Neighboring gene cocaine- and amphetamine-regulated transcript-like Neighboring gene CREB regulated transcription coactivator 3 Neighboring gene ADAMTS like 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005187582.1 Unplaced Scaffold Reference PunNye1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras GTPase-activating-like protein IQGAP1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pundamilia nyererei Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PunNye1.0

Genomic

  1. NW_005187582.1 Reference PunNye1.0

    Range
    636431..679241
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005746682.2 → XP_005746739.1  ras GTPase-activating-like protein IQGAP1

    UniProtKB/TrEMBL
    A0A3B4F2V3, A0A9Y3RUF7
    Related
    ENSPNYP00000004278.1, ENSPNYT00000004386.1
    Conserved Domains (6) summary
    smart00015
    Location:803 → 823
    IQ; Calmodulin-binding motif
    smart00323
    Location:989 → 1340
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:43 → 157
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00201
    Location:680 → 708
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam03836
    Location:1451 → 1576
    RasGAP_C; RasGAP C-terminus
    cl02569
    Location:1000 → 1379
    RasGAP; Ras GTPase Activating Domain
Nucleotide Protein
Heading Accession and Version

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