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GATA4 GATA binding protein 4 [ Capra hircus (goat) ]

Gene ID: 102186866, updated on 10-Mar-2024

Summary

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Gene symbol
GATA4
Gene description
GATA binding protein 4
See related
EnsemblRapid:ENSCHIG00000009574
Gene type
protein coding
RefSeq status
MODEL
Organism
Capra hircus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
12
Annotation release Status Assembly Chr Location
102 current ASM170441v1 (GCF_001704415.1) 8 NC_030815.1 (7489073..7560435, complement)
101 previous assembly CHIR_1.0 (GCF_000317765.1) 8 NC_022300.1 (7397212..7404476, complement)

Chromosome 8 - NC_030815.1Genomic Context describing neighboring genes Neighboring gene cathepsin B Neighboring gene farnesyl-diphosphate farnesyltransferase 1 Neighboring gene uncharacterized LOC108636607 Neighboring gene BLK proto-oncogene, Src family tyrosine kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of Liaoning cashmere goat transcriptome: sequencing, de novo assembly, functional annotation and comparative analysis. Liu H, et al. PLoS One, 2013. PMID 24130835, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA N-glycosylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell fate commitment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor GATA-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM170441v1 Primary Assembly

Genomic

  1. NC_030815.1 Reference ASM170441v1 Primary Assembly

    Range
    7489073..7560435 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018051833.1 → XP_017907322.1  transcription factor GATA-4 isoform X3

    UniProtKB/TrEMBL
    A0A452FZM0

  2. XM_018051834.1 → XP_017907323.1  transcription factor GATA-4 isoform X3

    UniProtKB/TrEMBL
    A0A452FZM0

  3. XM_018051831.1 → XP_017907320.1  transcription factor GATA-4 isoform X1

  4. XM_018051832.1 → XP_017907321.1  transcription factor GATA-4 isoform X2

    UniProtKB/TrEMBL
    A0A452E0B6
    Related
    ENSCHIP00000005452.1, ENSCHIT00000013141.1
    Conserved Domains (3) summary
    COG5641
    Location:267 → 382
    GAT1; GATA Zn-finger-containing transcription factor [Transcription]
    cd00202
    Location:270 → 321
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    pfam05349
    Location:1 → 205
    GATA-N; GATA-type transcription activator, N-terminal
Nucleotide Protein
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