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RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase [ Capra hircus (goat) ]

Gene ID: 102186047, updated on 10-Mar-2024

Summary

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Gene symbol
RFFL
Gene description
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
See related
EnsemblRapid:ENSCHIG00000012667
Gene type
protein coding
RefSeq status
MODEL
Organism
Capra hircus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Orthologs
human mouse all
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Genomic context

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See RFFL in Genome Data Viewer
Location:
chromosome: 19
Exon count:
8
Annotation release Status Assembly Chr Location
102 current ASM170441v1 (GCF_001704415.1) 19 NC_030826.1 (14637693..14711886)
101 previous assembly CHIR_1.0 (GCF_000317765.1) 19 NC_022311.1 (14336128..14409939)

Chromosome 19 - NC_030826.1Genomic Context describing neighboring genes Neighboring gene fibronectin type III domain containing 8 Neighboring gene RAD51 paralog D Neighboring gene microRNA mir-2331 Neighboring gene DNA ligase 3 Neighboring gene zinc finger protein 830

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K48-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase rififylin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM170441v1 Primary Assembly

Genomic

  1. NC_030826.1 Reference ASM170441v1 Primary Assembly

    Range
    14637693..14711886
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018064231.1 → XP_017919720.1  E3 ubiquitin-protein ligase rififylin isoform X1

    UniProtKB/TrEMBL
    A0A452EDA4

  2. XM_018064233.1 → XP_017919722.1  E3 ubiquitin-protein ligase rififylin isoform X2

    UniProtKB/TrEMBL
    A0A452ECW9, A0A452EDA4
    Related
    ENSCHIP00000048779.1, ENSCHIT00000058783.1

  3. XM_018064232.1 → XP_017919721.1  E3 ubiquitin-protein ligase rififylin isoform X1

    UniProtKB/TrEMBL
    A0A452EDA4
Nucleotide Protein
Heading Accession and Version

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