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IMPDH2 inosine monophosphate dehydrogenase 2 [ Capra hircus (goat) ]

Gene ID: 102184671, updated on 10-Mar-2024

Summary

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Gene symbol
IMPDH2
Gene description
inosine monophosphate dehydrogenase 2
See related
EnsemblRapid:ENSCHIG00000011336
Gene type
protein coding
RefSeq status
MODEL
Organism
Capra hircus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
15
Annotation release Status Assembly Chr Location
102 current ASM170441v1 (GCF_001704415.1) 22 NC_030829.1 (51035513..51040383)
101 previous assembly CHIR_1.0 (GCF_000317765.1) 22 NC_022314.1 (50726874..50731743)

Chromosome 22 - NC_030829.1Genomic Context describing neighboring genes Neighboring gene glutaminyl-tRNA synthetase 1 Neighboring gene glutamine rich 1 Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 3 Neighboring gene microRNA mir-191

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables IMP dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in GTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inosine-5'-monophosphate dehydrogenase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM170441v1 Primary Assembly

Genomic

  1. NC_030829.1 Reference ASM170441v1 Primary Assembly

    Range
    51035513..51040383
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013973506.2 → XP_013828960.1  inosine-5'-monophosphate dehydrogenase 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C2SJ22, A0A8C2SKG9
    Conserved Domains (3) summary
    cd00381
    Location:29 → 504
    IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
    cd04602
    Location:115 → 230
    CBS_pair_IMPDH_2; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a key ...
    PTZ00314
    Location:16 → 534
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional

  2. XM_005695973.2 → XP_005696030.1  inosine-5'-monophosphate dehydrogenase 2 isoform X2

    See identical proteins and their annotated locations for XP_005696030.1

    UniProtKB/TrEMBL
    A0A452E7M2, A0A8C2SKG9
    Related
    ENSCHIP00000008074.1, ENSCHIT00000015826.1
    Conserved Domains (1) summary
    PTZ00314
    Location:16 → 510
    PTZ00314; inosine-5'-monophosphate dehydrogenase; Provisional
Nucleotide Protein
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