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FGFR1 fibroblast growth factor receptor 1 [ Macaca fascicularis (crab-eating macaque) ]

Gene ID: 102144714, updated on 10-Mar-2024

Summary

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Gene symbol
FGFR1
Gene description
fibroblast growth factor receptor 1
See related
Ensembl:ENSMFAG00000034537
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca fascicularis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
24
Annotation release Status Assembly Chr Location
102 current MFA1912RKSv2 (GCF_012559485.2) 8 NC_052262.1 (37402198..37461827, complement)
101 previous assembly Macaca_fascicularis_5.0 (GCF_000364345.1) 8 NC_022279.1 (39231042..39290761, complement)

Chromosome 8 - NC_052262.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor binding SET domain protein 3 Neighboring gene leucine zipper and EF-hand containing transmembrane protein 2 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized protein C8orf86-like Neighboring gene uncharacterized LOC123575179

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroblast growth factor receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca fascicularis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MFA1912RKSv2 Primary Assembly

Genomic

  1. NC_052262.1 Reference MFA1912RKSv2 Primary Assembly

    Range
    37402198..37461827 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045399083.1 → XP_045255018.1  fibroblast growth factor receptor 1 isoform X30

  2. XM_045399073.1 → XP_045255008.1  fibroblast growth factor receptor 1 isoform X27

  3. XM_045399071.1 → XP_045255006.1  fibroblast growth factor receptor 1 isoform X25

  4. XM_045399061.1 → XP_045254996.1  fibroblast growth factor receptor 1 isoform X14

  5. XM_045399072.1 → XP_045255007.1  fibroblast growth factor receptor 1 isoform X26

  6. XM_045399070.1 → XP_045255005.1  fibroblast growth factor receptor 1 isoform X24

  7. XM_045399060.1 → XP_045254995.1  fibroblast growth factor receptor 1 isoform X13

  8. XM_045399069.1 → XP_045255004.1  fibroblast growth factor receptor 1 isoform X22

  9. XM_045399068.1 → XP_045255003.1  fibroblast growth factor receptor 1 isoform X21

  10. XM_045399053.1 → XP_045254988.1  fibroblast growth factor receptor 1 isoform X7

  11. XM_045399067.1 → XP_045255002.1  fibroblast growth factor receptor 1 isoform X20

  12. XM_045399052.1 → XP_045254987.1  fibroblast growth factor receptor 1 isoform X6

  13. XM_045399064.1 → XP_045254999.1  fibroblast growth factor receptor 1 isoform X17

  14. XM_045399059.1 → XP_045254994.1  fibroblast growth factor receptor 1 isoform X12

  15. XM_045399049.1 → XP_045254984.1  fibroblast growth factor receptor 1 isoform X3

  16. XM_045399063.1 → XP_045254998.1  fibroblast growth factor receptor 1 isoform X16

  17. XM_045399062.1 → XP_045254997.1  fibroblast growth factor receptor 1 isoform X15

  18. XM_045399057.1 → XP_045254992.1  fibroblast growth factor receptor 1 isoform X11

  19. XM_045399055.1 → XP_045254990.1  fibroblast growth factor receptor 1 isoform X9

  20. XM_045399054.1 → XP_045254989.1  fibroblast growth factor receptor 1 isoform X8

  21. XM_045399048.1 → XP_045254983.1  fibroblast growth factor receptor 1 isoform X2

  22. XM_045399047.1 → XP_045254982.1  fibroblast growth factor receptor 1 isoform X1

  23. XM_045399082.1 → XP_045255017.1  fibroblast growth factor receptor 1 isoform X30

  24. XM_045399075.1 → XP_045255010.1  fibroblast growth factor receptor 1 isoform X1

  25. XM_045399079.1 → XP_045255014.1  fibroblast growth factor receptor 1 isoform X14

  26. XM_045399078.1 → XP_045255013.1  fibroblast growth factor receptor 1 isoform X13

  27. XM_045399080.1 → XP_045255015.1  fibroblast growth factor receptor 1 isoform X22

  28. XM_045399077.1 → XP_045255012.1  fibroblast growth factor receptor 1 isoform X7

  29. XM_045399076.1 → XP_045255011.1  fibroblast growth factor receptor 1 isoform X6

  30. XM_045399074.1 → XP_045255009.1  fibroblast growth factor receptor 1 isoform X1

  31. XM_015454687.2 → XP_015310173.2  fibroblast growth factor receptor 1 isoform X29

    Conserved Domains (5) summary
    cd05098
    Location:372 → 673
    PTKc_FGFR1; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 1
    pfam18123
    Location:281 → 310
    FGFR3_TM; Fibroblast growth factor receptor 3 transmembrane domain
    cd00096
    Location:165 → 168
    Ig; Ig strand A [structural motif]
    cd05857
    Location:63 → 157
    IgI_2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; member of the I-set of IgSF domains
    cl11960
    Location:165 → 269
    Ig; Immunoglobulin domain

  32. XM_015454686.2 → XP_015310172.2  fibroblast growth factor receptor 1 isoform X28

    Conserved Domains (5) summary
    cd05098
    Location:374 → 675
    PTKc_FGFR1; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 1
    pfam18123
    Location:283 → 312
    FGFR3_TM; Fibroblast growth factor receptor 3 transmembrane domain
    cd00096
    Location:167 → 170
    Ig; Ig strand A [structural motif]
    cd05857
    Location:65 → 159
    IgI_2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; member of the I-set of IgSF domains
    cl11960
    Location:167 → 271
    Ig; Immunoglobulin domain

  33. XM_005563110.3 → XP_005563167.2  fibroblast growth factor receptor 1 isoform X31

    Conserved Domains (6) summary
    cd05098
    Location:463 → 764
    PTKc_FGFR1; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 1
    pfam18123
    Location:370 → 399
    FGFR3_TM; Fibroblast growth factor receptor 3 transmembrane domain
    cd00096
    Location:254 → 257
    Ig; Ig strand A [structural motif]
    cd04973
    Location:25 → 118
    IgI_1_FGFR; First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR); member of the I-set of Ig superfamily (IgSF) domains
    cd05857
    Location:152 → 246
    IgI_2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; member of the I-set of IgSF domains
    cl11960
    Location:254 → 358
    Ig; Immunoglobulin domain

  34. XM_005563111.3 → XP_005563168.2  fibroblast growth factor receptor 1 isoform X23

    Conserved Domains (6) summary
    cd05098
    Location:463 → 764
    PTKc_FGFR1; Catalytic domain of the Protein Tyrosine Kinase, Fibroblast Growth Factor Receptor 1
    pfam18123
    Location:372 → 401
    FGFR3_TM; Fibroblast growth factor receptor 3 transmembrane domain
    cd00096
    Location:256 → 259
    Ig; Ig strand A [structural motif]
    cd04973
    Location:25 → 118
    IgI_1_FGFR; First immunoglobulin (Ig)-like domain of fibroblast growth factor receptor (FGFR); member of the I-set of Ig superfamily (IgSF) domains
    cd05857
    Location:154 → 248
    IgI_2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; member of the I-set of IgSF domains
    cl11960
    Location:256 → 360
    Ig; Immunoglobulin domain

  35. XM_045399065.1 → XP_045255000.1  fibroblast growth factor receptor 1 isoform X18

  36. XM_045399066.1 → XP_045255001.1  fibroblast growth factor receptor 1 isoform X19

  37. XM_045399056.1 → XP_045254991.1  fibroblast growth factor receptor 1 isoform X10

  38. XM_045399051.1 → XP_045254986.1  fibroblast growth factor receptor 1 isoform X5

  39. XM_045399050.1 → XP_045254985.1  fibroblast growth factor receptor 1 isoform X4

Nucleotide Protein
Heading Accession and Version

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