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ECT2 epithelial cell transforming 2 [ Columba livia (rock pigeon) ]

Gene ID: 102089704, updated on 10-Mar-2024

Summary

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Gene symbol
ECT2
Gene description
epithelial cell transforming 2
Locus tag
A306_11983
Gene type
protein coding
RefSeq status
MODEL
Organism
Columba livia
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba
Orthologs
human mouse all
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Genomic context

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See ECT2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
102 current Cliv_1.0 (GCF_000337935.1) Unplaced Scaffold NW_004973751.1 (332808..362457, complement)

NW_004973751.1Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 16 Neighboring gene uncharacterized LOC110365919 Neighboring gene uncharacterized LOC110365920 Neighboring gene neutral cholesterol ester hydrolase 1 Neighboring gene uncharacterized LOC110365921

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004973751 Unplaced Scaffold Reference Cliv_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cytokinesis, actomyosin contractile ring assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein ECT2
Names
Protein ECT2
epithelial cell transforming sequence 2 oncogene

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Columba livia Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cliv_1.0 Primary Assembly

Genomic

  1. NW_004973751.1 Reference Cliv_1.0 Primary Assembly

    Range
    332808..362457 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005512006.3 → XP_005512063.1  protein ECT2 isoform X8

    UniProtKB/TrEMBL
    A0A2I0MBH0
    Conserved Domains (4) summary
    smart00325
    Location:425 → 609
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:600 → 773
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:235 → 310
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12738
    Location:148 → 211
    PTCB-BRCT; twin BRCT domain

  2. XM_021300548.1 → XP_021156223.1  protein ECT2 isoform X4

    Conserved Domains (4) summary
    smart00325
    Location:425 → 609
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:600 → 773
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:235 → 310
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12738
    Location:148 → 211
    PTCB-BRCT; twin BRCT domain

  3. XM_005512007.3 → XP_005512064.1  protein ECT2 isoform X6

    UniProtKB/TrEMBL
    A0A2I0MBG9
    Conserved Domains (4) summary
    smart00325
    Location:456 → 640
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:631 → 804
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:266 → 341
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12738
    Location:179 → 242
    PTCB-BRCT; twin BRCT domain

  4. XM_021300546.1 → XP_021156221.1  protein ECT2 isoform X2

    Conserved Domains (4) summary
    smart00325
    Location:456 → 640
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:631 → 804
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:266 → 341
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12738
    Location:179 → 242
    PTCB-BRCT; twin BRCT domain

  5. XM_021300551.1 → XP_021156226.1  protein ECT2 isoform X7

    Conserved Domains (4) summary
    smart00325
    Location:426 → 610
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:601 → 774
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:236 → 311
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12738
    Location:149 → 212
    PTCB-BRCT; twin BRCT domain

  6. XM_021300547.1 → XP_021156222.1  protein ECT2 isoform X3

    Conserved Domains (4) summary
    smart00325
    Location:426 → 610
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:601 → 774
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:236 → 311
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12738
    Location:149 → 212
    PTCB-BRCT; twin BRCT domain

  7. XM_021300549.1 → XP_021156224.1  protein ECT2 isoform X5

    Conserved Domains (4) summary
    smart00325
    Location:457 → 641
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:632 → 805
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:267 → 342
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12738
    Location:180 → 243
    PTCB-BRCT; twin BRCT domain

  8. XM_021300543.1 → XP_021156218.1  protein ECT2 isoform X1

    Conserved Domains (4) summary
    smart00325
    Location:457 → 641
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:632 → 805
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:267 → 342
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12738
    Location:180 → 243
    PTCB-BRCT; twin BRCT domain

  9. XM_021300544.1 → XP_021156219.1  protein ECT2 isoform X1

    Conserved Domains (4) summary
    smart00325
    Location:457 → 641
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:632 → 805
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:267 → 342
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam12738
    Location:180 → 243
    PTCB-BRCT; twin BRCT domain
Nucleotide Protein
Heading Accession and Version

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