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PSEN2 presenilin 2 [ Zonotrichia albicollis (white-throated sparrow) ]

Gene ID: 102068930, updated on 10-Mar-2024

Summary

Gene symbol
PSEN2
Gene description
presenilin 2
See related
Ensembl:ENSZALG00000006406
Gene type
protein coding
RefSeq status
MODEL
Organism
Zonotrichia albicollis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Passerellidae; Zonotrichia
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
102 current Zonotrichia_albicollis-1.0.1 (GCF_000385455.1) Unplaced Scaffold NW_005081602.1 (769336..786951, complement)

NW_005081602.1Genomic Context describing neighboring genes Neighboring gene xanthine dehydrogenase Neighboring gene CDC42 binding protein kinase alpha Neighboring gene coenzyme Q8A Neighboring gene inositol-trisphosphate 3-kinase B Neighboring gene stum, mechanosensory transduction mediator homolog

Genomic regions, transcripts, and products

Genomic Sequence:
NW_005081602 Unplaced Scaffold Reference Zonotrichia_albicollis-1.0.1

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in amyloid precursor protein catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in calcium ion transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in ciliary rootlet IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in dendritic shaft IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
presenilin-2
Names
presenilin 2 (Alzheimer disease 4)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Zonotrichia albicollis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Zonotrichia_albicollis-1.0.1

Genomic

  1. NW_005081602.1 Reference Zonotrichia_albicollis-1.0.1

    Range
    769336..786951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005488473.3XP_005488530.1  presenilin-2

    See identical proteins and their annotated locations for XP_005488530.1

    UniProtKB/TrEMBL
    A0A8D2MGH3
    Related
    ENSZALP00000007166.1, ENSZALT00000010300.1
    Conserved Domains (1) summary
    pfam01080
    Location:88447
    Presenilin; Presenilin