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NSD2 nuclear receptor binding SET domain protein 2 [ Zonotrichia albicollis (white-throated sparrow) ]

Gene ID: 102062837, updated on 10-Mar-2024

Summary

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Gene symbol
NSD2
Gene description
nuclear receptor binding SET domain protein 2
See related
Ensembl:ENSZALG00000007532
Gene type
protein coding
RefSeq status
MODEL
Organism
Zonotrichia albicollis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Passerellidae; Zonotrichia
Also known as
WHSC1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
102 current Zonotrichia_albicollis-1.0.1 (GCF_000385455.1) Unplaced Scaffold NW_005081566.1 (2355605..2455242, complement)

NW_005081566.1Genomic Context describing neighboring genes Neighboring gene negative elongation factor complex member A Neighboring gene mucin-2 Neighboring gene small Cajal body-specific RNA 23 Neighboring gene leucine zipper and EF-hand containing transmembrane protein 1 Neighboring gene coiled-coil domain-containing protein 42-like Neighboring gene fibroblast growth factor receptor 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005081566 Unplaced Scaffold Reference Zonotrichia_albicollis-1.0.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K36 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase NSD2
Names
Wolf-Hirschhorn syndrome candidate 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Zonotrichia albicollis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Zonotrichia_albicollis-1.0.1

Genomic

  1. NW_005081566.1 Reference Zonotrichia_albicollis-1.0.1

    Range
    2355605..2455242 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014266087.2 → XP_014121562.1  histone-lysine N-methyltransferase NSD2 isoform X1

    UniProtKB/TrEMBL
    A0A8D2MKK2
    Conserved Domains (10) summary
    cd05837
    Location:219 → 338
    MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
    cd05838
    Location:943 → 1037
    WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
    smart00570
    Location:1077 → 1127
    AWS; associated with SET domains
    smart00317
    Location:1128 → 1251
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd00084
    Location:462 → 511
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd15651
    Location:781 → 827
    PHD2_NSD2; PHD finger 2 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15654
    Location:828 → 881
    PHD3_NSD2; PHD finger 3 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15657
    Location:898 → 938
    PHD4_NSD2; PHD finger 4 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15660
    Location:1306 → 1348
    PHD5_NSD2; PHD finger 5 found in nuclear SET domain-containing protein 2 (NSD2)
    cl22851
    Location:734 → 776
    PHD_SF; PHD finger superfamily

  2. XM_026792636.1 → XP_026648437.1  histone-lysine N-methyltransferase NSD2 isoform X2

    UniProtKB/TrEMBL
    A0A8D2MK18, A0A8D2MKK2
    Related
    ENSZALP00000008675.1, ENSZALT00000012219.1

  3. XM_026792637.1 → XP_026648438.1  histone-lysine N-methyltransferase NSD2 isoform X3

    UniProtKB/TrEMBL
    A0A8D2MKK2
    Related
    ENSZALP00000008676.1, ENSZALT00000012220.1

  4. XM_026792635.1 → XP_026648436.1  histone-lysine N-methyltransferase NSD2 isoform X1

    UniProtKB/TrEMBL
    A0A8D2MKK2
Nucleotide Protein
Heading Accession and Version

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