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IGF1R insulin like growth factor 1 receptor [ Geospiza fortis (medium ground-finch) ]

Gene ID: 102036037, updated on 10-Mar-2024

Summary

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Gene symbol
IGF1R
Gene description
insulin like growth factor 1 receptor
See related
Ensembl:ENSGFOG00000013193
Gene type
protein coding
RefSeq status
MODEL
Organism
Geospiza fortis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Thraupidae; Geospiza
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
102 current GeoFor_1.0 (GCF_000277835.1) Unplaced Scaffold NW_005054366.1 (160922..331409, complement)

NW_005054366.1Genomic Context describing neighboring genes Neighboring gene crooked neck-like protein 1 Neighboring gene pyroglutamyl-peptidase I like Neighboring gene synemin Neighboring gene leucine rich repeat containing 28

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_005054366 Unplaced Scaffold Reference GeoFor_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin receptor substrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol 3-kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in insulin-like growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of insulin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin-like growth factor 1 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Geospiza fortis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GeoFor_1.0

Genomic

  1. NW_005054366.1 Reference GeoFor_1.0

    Range
    160922..331409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005424221.2 → XP_005424278.2  insulin-like growth factor 1 receptor isoform X1

    UniProtKB/TrEMBL
    A0A6I9HMQ6
    Related
    ENSGFOP00000019619.1, ENSGFOT00000020255.1
    Conserved Domains (4) summary
    cd00063
    Location:860 → 949
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00757
    Location:200 → 358
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:376 → 489
    Recep_L_domain; Receptor L domain
    cl21453
    Location:1018 → 1305
    PKc_like; Protein Kinases, catalytic domain

  2. XM_005424222.2 → XP_005424279.2  insulin-like growth factor 1 receptor isoform X2

    UniProtKB/TrEMBL
    A0A6I9HMI6
    Conserved Domains (4) summary
    cd00063
    Location:860 → 949
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00757
    Location:200 → 358
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:376 → 489
    Recep_L_domain; Receptor L domain
    cl21453
    Location:1017 → 1304
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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