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Hspg2 heparan sulfate proteoglycan 2 [ Microtus ochrogaster (prairie vole) ]

Gene ID: 102001736, updated on 10-Mar-2024

Summary

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Gene symbol
Hspg2
Gene description
heparan sulfate proteoglycan 2
See related
Ensembl:ENSMOCG00000008848
Gene type
protein coding
RefSeq status
MODEL
Organism
Microtus ochrogaster
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Arvicolinae; Microtus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
96
Annotation release Status Assembly Chr Location
102 current MicOch1.0 (GCF_000317375.1) 10 NC_022016.1 (47294223..47396577, complement)

Chromosome 10 - NC_022016.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 48 Neighboring gene low density lipoprotein receptor class A domain containing 2 Neighboring gene uncharacterized LOC102002005 Neighboring gene chymotrypsin-like elastase family member 3B

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_022016.1 Chromosome 10 Reference MicOch1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: basement membrane-specific heparan sulfate proteoglycan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microtus ochrogaster Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MicOch1.0

Genomic

  1. NC_022016.1 Reference MicOch1.0

    Range
    47294223..47396577 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013348417.2 → XP_013203871.1  LOW QUALITY PROTEIN: basement membrane-specific heparan sulfate proteoglycan core protein

    UniProtKB/TrEMBL
    A0A8J6G2I5
    Related
    ENSMOCP00000008864.1, ENSMOCT00000011478.1
    Conserved Domains (16) summary
    cd05743
    Location:419 → 496
    Ig_Perlecan_D2_like; Immunoglobulin (Ig)-like domain II (D2) of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2
    cd05754
    Location:1774 → 1859
    Ig3_Perlecan_like; Third immunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00408
    Location:2647 → 2706
    IGc2; Immunoglobulin C-2 Type
    smart00281
    Location:1397 → 1520
    LamB; Laminin B domain
    smart00409
    Location:3221 → 3295
    IG; Immunoglobulin
    smart00410
    Location:2351 → 2428
    IG_like; Immunoglobulin like
    cd00054
    Location:3848 → 3881
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:762 → 804
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:4203 → 4361
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:283 → 317
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:1959 → 2045
    I-set; Immunoglobulin I-set domain
    pfam00047
    Location:3027 → 3107
    ig; Immunoglobulin domain
    pfam00053
    Location:1279 → 1326
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:198 → 233
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    cl02507
    Location:79 → 186
    SEA; SEA domain
    cl11960
    Location:3581 → 3658
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version

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