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Ntrk1 neurotrophic receptor tyrosine kinase 1 [ Microtus ochrogaster (prairie vole) ]

Gene ID: 101994684, updated on 11-Apr-2024

Summary

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Gene symbol
Ntrk1
Gene description
neurotrophic receptor tyrosine kinase 1
See related
Ensembl:ENSMOCG00000001237
Gene type
protein coding
RefSeq status
MODEL
Organism
Microtus ochrogaster
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Arvicolinae; Microtus
Orthologs
human mouse all
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Genomic context

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See Ntrk1 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
17
Annotation release Status Assembly Chr Location
102 current MicOch1.0 (GCF_000317375.1) 21 NC_022022.1 (1007816..1023849)

Chromosome 21 - NC_022022.1Genomic Context describing neighboring genes Neighboring gene SH2 domain containing 2A Neighboring gene insulin receptor related receptor Neighboring gene platelet endothelial aggregation receptor 1 Neighboring gene leucine rich repeat containing 71

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_022022.1 Chromosome 21 Reference MicOch1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotrophin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotrophin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to nerve growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nerve growth factor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
high affinity nerve growth factor receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microtus ochrogaster Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MicOch1.0

Genomic

  1. NC_022022.1 Reference MicOch1.0

    Range
    1007816..1023849
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005356909.2 → XP_005356966.1  high affinity nerve growth factor receptor

    UniProtKB/TrEMBL
    A0A8J6KWP9
    Related
    ENSMOCP00000001620.1, ENSMOCT00000001691.1
    Conserved Domains (8) summary
    cd04971
    Location:301 → 382
    Ig_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd04972
    Location:197 → 284
    Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    smart00221
    Location:513 → 784
    STYKc; Protein kinase; unclassified specificity
    pfam07679
    Location:196 → 284
    I-set; Immunoglobulin I-set domain
    sd00031
    Location:68 → 92
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:92 → 150
    LRR_8; Leucine rich repeat
    cl15307
    Location:152 → 194
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl21453
    Location:507 → 786
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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