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LOC101987367 NADPH--cytochrome P450 reductase [ Microtus ochrogaster (prairie vole) ]

Gene ID: 101987367, updated on 8-Mar-2024

Summary

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Gene symbol
LOC101987367
Gene description
NADPH--cytochrome P450 reductase
See related
Ensembl:ENSMOCG00000000571
Gene type
protein coding
RefSeq status
MODEL
Organism
Microtus ochrogaster
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Arvicolinae; Microtus
Also known as
Por
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
19
Annotation release Status Assembly Chr Location
102 current MicOch1.0 (GCF_000317375.1) 2 NC_022010.1 (21852992..21896984, complement)

Chromosome 2 - NC_022010.1Genomic Context describing neighboring genes Neighboring gene serine/threonine/tyrosine interacting like 1 Neighboring gene transmembrane protein 120A Neighboring gene rhomboid domain containing 2 Neighboring gene C-C motif chemokine ligand 24

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_022010.1 Chromosome 2 Reference MicOch1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FMN binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables NADPH-hemoprotein reductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in response to hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NADPH--cytochrome P450 reductase
Names
P450 (cytochrome) oxidoreductase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microtus ochrogaster Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MicOch1.0

Genomic

  1. NC_022010.1 Reference MicOch1.0

    Range
    21852992..21896984 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005344609.3 → XP_005344666.1  NADPH--cytochrome P450 reductase isoform X1

    See identical proteins and their annotated locations for XP_005344666.1

    UniProtKB/TrEMBL
    A0A8J6KRA4
    Related
    ENSMOCP00000000721.1, ENSMOCT00000000752.1
    Conserved Domains (3) summary
    cd06204
    Location:277 → 677
    CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
    COG0369
    Location:52 → 677
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    pfam00258
    Location:82 → 219
    Flavodoxin_1; Flavodoxin

  2. XM_013350716.2 → XP_013206170.1  NADPH--cytochrome P450 reductase isoform X1

    UniProtKB/TrEMBL
    A0A8J6KRA4
    Conserved Domains (3) summary
    cd06204
    Location:277 → 677
    CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
    COG0369
    Location:52 → 677
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    pfam00258
    Location:82 → 219
    Flavodoxin_1; Flavodoxin

  3. XM_005344610.3 → XP_005344667.1  NADPH--cytochrome P450 reductase isoform X1

    See identical proteins and their annotated locations for XP_005344667.1

    UniProtKB/TrEMBL
    A0A8J6KRA4
    Conserved Domains (3) summary
    cd06204
    Location:277 → 677
    CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
    COG0369
    Location:52 → 677
    CysJ; Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]
    pfam00258
    Location:82 → 219
    Flavodoxin_1; Flavodoxin

  4. XM_026784738.1 → XP_026640539.1  NADPH--cytochrome P450 reductase isoform X2

    UniProtKB/TrEMBL
    A0A8J6KRA4
    Conserved Domains (2) summary
    cd06204
    Location:232 → 632
    CYPOR; NADPH cytochrome p450 reductase (CYPOR) serves as an electron donor in several oxygenase systems and is a component of nitric oxide synthases and methionine synthase reductases. CYPOR transfers two electrons from NADPH to the heme of cytochrome p450 via ...
    pfam00258
    Location:37 → 174
    Flavodoxin_1
Nucleotide Protein
Heading Accession and Version

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