MPHOSPH9 M-phase phosphoprotein 9 [Homo sapiens] - Gene

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Summary

Official Symbol: MPHOSPH9provided by HGNC
Official Full Name: M-phase phosphoprotein 9provided by HGNC
Primary source: HGNC:7215
See related: Ensembl:ENSG00000051825; HPRD:12022; MIM:605501; Vega:OTTHUMG00000168849
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: MPP9; MPP-9; FLJ12954; DKFZp434J034

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Genomic context

Location :: 12q24.31

Sequence :: Chromosome: 12; NC_000012.11 (123640946..123706441, complement)

See MPHOSPH9 in Epigenomics, MapViewer

Chromosome 12 - NC_000012.11 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
Title: An application of Random Forests to a genome-wide association dataset: methodological considerations & new findings.
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score.

Submit: New GeneRIF Correction

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Phenotypes

Review eQTL and phenotype association data in this region using PheGenI

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.

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Products	Interactant	Other Gene	Source	Pubs	Description
BioGRID:115493	BioGRID:112707	SVIL	BioGRID	PubMed	Two-hybrid
BioGRID:115493	BioGRID:113164	UBC	BioGRID	PubMed	Reconstituted Complex
BioGRID:115493	BioGRID:113866	USP11	BioGRID	PubMed	Affinity Capture-MS
BioGRID:115493	BioGRID:113364	YWHAG	BioGRID	PubMed	Two-hybrid
BioGRID:115493	BioGRID:113366	YWHAZ	BioGRID	PubMed	Two-hybrid

Process	Evidence Code	Pubs
M phase of mitotic cell cycle	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
Golgi apparatus	IEA Inferred from Electronic Annotation more info
Golgi membrane	IEA Inferred from Electronic Annotation more info
centriole	IEA Inferred from Electronic Annotation more info
cytoplasm	IEA Inferred from Electronic Annotation more info
cytoskeleton	IEA Inferred from Electronic Annotation more info
membrane	IEA Inferred from Electronic Annotation more info

General protein information

Preferred Names: M-phase phosphoprotein 9

Names: M-phase phosphoprotein 9

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_022782.2 → NP_073619.2 M-phase phosphoprotein 9

Status: VALIDATED

Source sequence(s)

AK091181, AK096541, BU070541, BX092492, X98258

Consensus CDS

CCDS9243.1

UniProtKB/Swiss-Prot

Q99550

Related

ENSP00000445859, OTTHUMP00000239617, ENST00000541076, OTTHUMT00000401355

Conserved Domains (1) summary

TIGR02168
Location:440 – 646
Blast Score: 144

SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: Build 37.3

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p5 Primary Assembly

Genomic

NC_000012.11 Reference GRCh37.p5 Primary Assembly

Range

123640946..123706441, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000144.1 Alternate HuRef

Range

120601582..120667310, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	AC073857.30 (15619..81114)	None
genomic	CH471054.1	EAW98388.1
		EAW98389.1
		EAW98390.1
		EAW98391.1
		EAW98392.1
		EAW98393.1
		EAW98394.1
mRNA	AK023016.1	BAB14359.1
mRNA	AK091181.1	BAG52299.1
mRNA	AK096541.1	None
mRNA	AL096751.1	None
mRNA	BC130440.1	AAI30441.1
mRNA	BC144016.1	None
mRNA	BC144017.1	None
mRNA	BU070541.1	None
mRNA	BX092492.1	None
mRNA	X98258.1	CAA66911.1