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Wnk4 WNK lysine deficient protein kinase 4 [ Ictidomys tridecemlineatus (thirteen-lined ground squirrel) ]

Gene ID: 101971771, updated on 8-Mar-2024

Summary

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Gene symbol
Wnk4
Gene description
WNK lysine deficient protein kinase 4
Locus tag
H1C71_021828
See related
EnsemblRapid:ENSSTOG00015022287
Gene type
protein coding
RefSeq status
MODEL
Organism
Ictidomys tridecemlineatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
103 current HiC_Itri_2 (GCF_016881025.1) Unplaced Scaffold NW_024405602.1 (19567157..19582658, complement)
102 previous assembly SpeTri2.0 (GCF_000236235.1) Unplaced Scaffold NW_004936490.1 (17492718..17508571)

NW_024405602.1Genomic Context describing neighboring genes Neighboring gene cyclin N-terminal domain containing 1 Neighboring gene cytochrome c oxidase assembly factor 3 homolog, mitochondrial Neighboring gene vacuolar protein sorting 25 homolog Neighboring gene receptor activity modifying protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chloride channel inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of sodium ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of sodium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in renal sodium ion absorption IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase WNK4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ictidomys tridecemlineatus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HiC_Itri_2 Primary Assembly

Genomic

  1. NW_024405602.1 Reference HiC_Itri_2 Primary Assembly

    Range
    19567157..19582658 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040268749.1 → XP_040124683.1  serine/threonine-protein kinase WNK4 isoform X1

    UniProtKB/TrEMBL
    I3M342
    Conserved Domains (3) summary
    PHA03247
    Location:749 → 1091
    PHA03247; large tegument protein UL36; Provisional
    cd14033
    Location:171 → 431
    STKc_WNK4; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 4
    pfam12202
    Location:452 → 514
    OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

  2. XM_040268750.1 → XP_040124684.1  serine/threonine-protein kinase WNK4 isoform X3

    UniProtKB/TrEMBL
    I3M342
    Conserved Domains (1) summary
    cd14033
    Location:171 → 431
    STKc_WNK4; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 4

  3. XM_040268751.1 → XP_040124685.1  serine/threonine-protein kinase WNK4 isoform X4

    UniProtKB/TrEMBL
    I3M342
    Conserved Domains (1) summary
    cd14033
    Location:171 → 431
    STKc_WNK4; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 4

  4. XM_005321895.3 → XP_005321952.1  serine/threonine-protein kinase WNK4 isoform X2

    UniProtKB/TrEMBL
    A0A287CTE7, I3M342
    Related
    ENSSTOP00015027535.1, ENSSTOT00015029928.1
    Conserved Domains (3) summary
    PHA03247
    Location:749 → 1091
    PHA03247; large tegument protein UL36; Provisional
    cd14033
    Location:171 → 431
    STKc_WNK4; Catalytic domain of the Serine/Threonine protein kinase, With No Lysine (WNK) 4
    pfam12202
    Location:452 → 514
    OSR1_C; Oxidative-stress-responsive kinase 1 C-terminal domain

RNA

  1. XR_005726288.1 RNA Sequence

  2. XR_005726286.1 RNA Sequence

  3. XR_005726285.1 RNA Sequence

  4. XR_001229666.3 RNA Sequence

  5. XR_002483580.2 RNA Sequence

  6. XR_005726287.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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