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Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 [ Ictidomys tridecemlineatus (thirteen-lined ground squirrel) ]

Gene ID: 101965386, updated on 8-Mar-2024

Summary

Gene symbol
Asap3
Gene description
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
Locus tag
H1C71_032990
See related
EnsemblRapid:ENSSTOG00015013226
Gene type
protein coding
RefSeq status
MODEL
Organism
Ictidomys tridecemlineatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
103 current HiC_Itri_2 (GCF_016881025.1) Unplaced Scaffold NW_024405058.1 (42821130..42864740, complement)
102 previous assembly SpeTri2.0 (GCF_000236235.1) Unplaced Scaffold NW_004936474.1 (8645917..8689511, complement)

NW_024405058.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120890666 Neighboring gene zinc finger protein 436 Neighboring gene transcription elongation factor A3 Neighboring gene actin-related protein 2/3 complex subunit 2-like Neighboring gene E2F transcription factor 2

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ictidomys tridecemlineatus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HiC_Itri_2 Primary Assembly

Genomic

  1. NW_024405058.1 Reference HiC_Itri_2 Primary Assembly

    Range
    42821130..42864740 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040288097.1XP_040144031.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X2

    Conserved Domains (6) summary
    PHA03307
    Location:727896
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0666
    Location:601698
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13251
    Location:311417
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:568594
    ANK; ANK repeat [structural motif]
    cd17900
    Location:441561
    ArfGap_ASAP3; ArfGAP domain of ASAP3 (ArfGAP with ANK repeat and PH domain-containing protein 3)
    cl12013
    Location:35260
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  2. XM_040288096.1XP_040144030.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X1

    Conserved Domains (6) summary
    PHA03307
    Location:729898
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0666
    Location:603700
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13251
    Location:313419
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:570596
    ANK; ANK repeat [structural motif]
    cd17900
    Location:443563
    ArfGap_ASAP3; ArfGAP domain of ASAP3 (ArfGAP with ANK repeat and PH domain-containing protein 3)
    cl12013
    Location:35260
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  3. XM_021734229.2XP_021589904.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X3

    Conserved Domains (6) summary
    cd07640
    Location:35243
    BAR_ASAP3; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 3
    PHA03307
    Location:712881
    PHA03307; transcriptional regulator ICP4; Provisional
    cd13251
    Location:296402
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:553579
    ANK; ANK repeat [structural motif]
    cd17900
    Location:426546
    ArfGap_ASAP3; ArfGAP domain of ASAP3 (ArfGAP with ANK repeat and PH domain-containing protein 3)
    pfam12796
    Location:592677
    Ank_2; Ankyrin repeats (3 copies)
  4. XM_005317588.4XP_005317645.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X4

    UniProtKB/TrEMBL
    I3MDS4
    Related
    ENSSTOP00015016152.1, ENSSTOT00015017737.1
    Conserved Domains (6) summary
    cd07640
    Location:35243
    BAR_ASAP3; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 3
    PHA03307
    Location:710879
    PHA03307; transcriptional regulator ICP4; Provisional
    cd13251
    Location:294400
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:551577
    ANK; ANK repeat [structural motif]
    cd17900
    Location:424544
    ArfGap_ASAP3; ArfGAP domain of ASAP3 (ArfGAP with ANK repeat and PH domain-containing protein 3)
    pfam12796
    Location:590675
    Ank_2; Ankyrin repeats (3 copies)
  5. XM_040288099.1XP_040144033.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X5

    Conserved Domains (6) summary
    PHA03307
    Location:581750
    PHA03307; transcriptional regulator ICP4; Provisional
    cd13251
    Location:165271
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:422448
    ANK; ANK repeat [structural motif]
    cd17900
    Location:295415
    ArfGap_ASAP3; ArfGAP domain of ASAP3 (ArfGAP with ANK repeat and PH domain-containing protein 3)
    pfam12796
    Location:461546
    Ank_2; Ankyrin repeats (3 copies)
    cl12013
    Location:1112
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  6. XM_040288098.1XP_040144032.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X5

    Conserved Domains (6) summary
    PHA03307
    Location:581750
    PHA03307; transcriptional regulator ICP4; Provisional
    cd13251
    Location:165271
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:422448
    ANK; ANK repeat [structural motif]
    cd17900
    Location:295415
    ArfGap_ASAP3; ArfGAP domain of ASAP3 (ArfGAP with ANK repeat and PH domain-containing protein 3)
    pfam12796
    Location:461546
    Ank_2; Ankyrin repeats (3 copies)
    cl12013
    Location:1112
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  7. XM_040288101.1XP_040144035.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X7

    Conserved Domains (5) summary
    PHA03307
    Location:437606
    PHA03307; transcriptional regulator ICP4; Provisional
    COG0666
    Location:311408
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13251
    Location:21127
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:278304
    ANK; ANK repeat [structural motif]
    cd17900
    Location:151271
    ArfGap_ASAP3; ArfGAP domain of ASAP3 (ArfGAP with ANK repeat and PH domain-containing protein 3)
  8. XM_040288100.1XP_040144034.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X6

    Conserved Domains (5) summary
    COG0666
    Location:603700
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd13251
    Location:313419
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:570596
    ANK; ANK repeat [structural motif]
    cd17900
    Location:443565
    ArfGap_ASAP3; ArfGAP domain of ASAP3 (ArfGAP with ANK repeat and PH domain-containing protein 3)
    cl12013
    Location:35260
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

RNA

  1. XR_005735025.1 RNA Sequence