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Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [ Ictidomys tridecemlineatus (thirteen-lined ground squirrel) ]

Gene ID: 101964573, updated on 8-Mar-2024

Summary

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Gene symbol
Mthfd2
Gene description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Locus tag
H1C71_034467
See related
EnsemblRapid:ENSSTOG00015011345
Gene type
protein coding
RefSeq status
MODEL
Organism
Ictidomys tridecemlineatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Ictidomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
103 current HiC_Itri_2 (GCF_016881025.1) Unplaced Scaffold NW_024406292.1 (10262753..10274900, complement)
102 previous assembly SpeTri2.0 (GCF_000236235.1) Unplaced Scaffold NW_004936556.1 (462998..475092)

NW_024406292.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110598561 Neighboring gene dynactin subunit 1 Neighboring gene solute carrier family 4 member 5 Neighboring gene MOB kinase activator 1A Neighboring gene bolA family member 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables methenyltetrahydrofolate cyclohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ictidomys tridecemlineatus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HiC_Itri_2 Primary Assembly

Genomic

  1. NW_024406292.1 Reference HiC_Itri_2 Primary Assembly

    Range
    10262753..10274900 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005329355.4 → XP_005329412.1  bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

    UniProtKB/TrEMBL
    I3LXP3
    Related
    ENSSTOP00015013939.1, ENSSTOT00015015266.1
    Conserved Domains (1) summary
    COG0190
    Location:39 → 333
    FolD; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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