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APH1B aph-1 homolog B, gamma-secretase subunit [ Chrysemys picta (Painted turtle) ]

Gene ID: 101949439, updated on 8-Mar-2024

Summary

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Gene symbol
APH1B
Gene description
aph-1 homolog B, gamma-secretase subunit
See related
Ensembl:ENSCPBG00000017813
Gene type
protein coding
RefSeq status
MODEL
Organism
Chrysemys picta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Emydidae; Chrysemys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
7
Annotation release Status Assembly Chr Location
103 current Chrysemys_picta_BioNano-3.0.4 (GCF_000241765.4) 9 NC_056657.1 (93123977..93140901, complement)
102 previous assembly Chrysemys_picta_bellii-3.0.3 (GCF_000241765.3) Unplaced Scaffold NW_007359888.1 (9492846..9509639)

Chromosome 9 - NC_056657.1Genomic Context describing neighboring genes Neighboring gene kunitz-type serine protease inhibitor bitisilin-3-like Neighboring gene carbonic anhydrase 12 Neighboring gene RAB8B, member RAS oncogene family Neighboring gene ribosomal protein S27 like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-macromolecule adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of gamma-secretase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gamma-secretase subunit APH-1B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chrysemys picta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Chrysemys_picta_BioNano-3.0.4 Primary Assembly

Genomic

  1. NC_056657.1 Reference Chrysemys_picta_BioNano-3.0.4 Primary Assembly

    Range
    93123977..93140901 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005285065.3 → XP_005285122.1  gamma-secretase subunit APH-1B isoform X2

    Conserved Domains (1) summary
    pfam06105
    Location:2 → 192
    Aph-1; Aph-1 protein

  2. XM_005285064.4 → XP_005285121.1  gamma-secretase subunit APH-1B isoform X1

    UniProtKB/TrEMBL
    A0A8C3HX53
    Related
    ENSCPBP00000025039.1
    Conserved Domains (1) summary
    pfam06105
    Location:2 → 233
    Aph-1; Aph-1 protein

  3. XM_005285066.4 → XP_005285123.1  gamma-secretase subunit APH-1B isoform X4

    Conserved Domains (1) summary
    pfam06105
    Location:2 → 201
    Aph-1; Aph-1 protein

  4. XM_042853809.1 → XP_042709743.1  gamma-secretase subunit APH-1B isoform X3

Nucleotide Protein
Heading Accession and Version

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