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ARHGEF18 Rho/Rac guanine nucleotide exchange factor 18 [ Chrysemys picta (Painted turtle) ]

Gene ID: 101947042, updated on 8-Mar-2024

Summary

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Gene symbol
ARHGEF18
Gene description
Rho/Rac guanine nucleotide exchange factor 18
See related
Ensembl:ENSCPBG00000012967
Gene type
protein coding
RefSeq status
MODEL
Organism
Chrysemys picta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Emydidae; Chrysemys
Orthologs
human mouse all
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Genomic context

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See ARHGEF18 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
32
Annotation release Status Assembly Chr Location
103 current Chrysemys_picta_BioNano-3.0.4 (GCF_000241765.4) Unplaced Scaffold NW_024885804.1 (5435566..5522568, complement)
102 previous assembly Chrysemys_picta_bellii-3.0.3 (GCF_000241765.3) Unplaced Scaffold NW_007281415.1 (3238577..3303714, complement)

NW_024885804.1Genomic Context describing neighboring genes Neighboring gene stabilizer of axonemal microtubules 5 Neighboring gene peroxisomal biogenesis factor 11 gamma Neighboring gene insulin receptor Neighboring gene uncharacterized LOC122174842

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 18

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chrysemys picta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Chrysemys_picta_BioNano-3.0.4 Primary Assembly

Genomic

  1. NW_024885804.1 Reference Chrysemys_picta_BioNano-3.0.4 Primary Assembly

    Range
    5435566..5522568 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008171589.2 → XP_008169811.2  rho guanine nucleotide exchange factor 18 isoform X6

    UniProtKB/TrEMBL
    A0A8C3HGP8
    Conserved Domains (4) summary
    smart00109
    Location:398 → 444
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    cd00160
    Location:599 → 793
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02168
    Location:1165 → 1297
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15794
    Location:833 → 951
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain

  2. XM_042862015.1 → XP_042717949.1  rho guanine nucleotide exchange factor 18 isoform X5

    UniProtKB/TrEMBL
    A0A8C3HGP8
    Conserved Domains (5) summary
    smart00109
    Location:464 → 510
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    COG4372
    Location:1223 → 1473
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    cd00160
    Location:665 → 859
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02168
    Location:1212 → 1344
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15794
    Location:899 → 1017
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain

  3. XM_005279019.2 → XP_005279076.2  rho guanine nucleotide exchange factor 18 isoform X4

    UniProtKB/TrEMBL
    A0A8C3HGP8
    Conserved Domains (5) summary
    smart00109
    Location:464 → 510
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    COG4372
    Location:1240 → 1490
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    cd00160
    Location:663 → 857
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02168
    Location:1229 → 1361
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15794
    Location:897 → 1015
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain

  4. XM_008171590.2 → XP_008169812.2  rho guanine nucleotide exchange factor 18 isoform X2

    UniProtKB/TrEMBL
    A0A8C3HGP8
    Conserved Domains (5) summary
    smart00109
    Location:464 → 510
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    COG4372
    Location:1241 → 1491
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    cd00160
    Location:664 → 858
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02168
    Location:1230 → 1362
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15794
    Location:898 → 1016
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain

  5. XM_005279018.2 → XP_005279075.2  rho guanine nucleotide exchange factor 18 isoform X3

    UniProtKB/TrEMBL
    A0A8C3HGP8
    Conserved Domains (5) summary
    smart00109
    Location:464 → 510
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    COG4372
    Location:1241 → 1491
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    cd00160
    Location:664 → 858
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02168
    Location:1230 → 1362
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15794
    Location:898 → 1016
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain

  6. XM_042862014.1 → XP_042717948.1  rho guanine nucleotide exchange factor 18 isoform X1

    UniProtKB/TrEMBL
    A0A8C3HGP8
    Conserved Domains (5) summary
    smart00109
    Location:464 → 510
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    COG4372
    Location:1242 → 1492
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    cd00160
    Location:665 → 859
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02168
    Location:1231 → 1363
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    cd15794
    Location:899 → 1017
    PH_ARHGEF18; Rho guanine nucleotide exchange factor 18 Pleckstrin homology (PH) domain
Nucleotide Protein
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