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MUTYH mutY DNA glycosylase [ Chrysemys picta (Painted turtle) ]

Gene ID: 101936029, updated on 8-Mar-2024

Summary

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Gene symbol
MUTYH
Gene description
mutY DNA glycosylase
Gene type
protein coding
RefSeq status
MODEL
Organism
Chrysemys picta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Emydidae; Chrysemys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Chrysemys_picta_BioNano-3.0.4 (GCF_000241765.4) Unplaced Scaffold NW_024885899.1 (7218419..7236809)
102 previous assembly Chrysemys_picta_bellii-3.0.3 (GCF_000241765.3) 8 NC_024225.1 (48294987..48313328, complement)

NW_024885899.1Genomic Context describing neighboring genes Neighboring gene testis associated actin remodelling kinase 2 Neighboring gene target of EGR1, exonuclease Neighboring gene selenoprotein Pb-like Neighboring gene 4-hydroxyphenylpyruvate dioxygenase like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables adenine/guanine mispair binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidized purine DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables purine-specific mismatch base pair DNA N-glycosylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in base-excision repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mismatch repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
adenine DNA glycosylase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chrysemys picta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Chrysemys_picta_BioNano-3.0.4 Primary Assembly

Genomic

  1. NW_024885899.1 Reference Chrysemys_picta_BioNano-3.0.4 Primary Assembly

    Range
    7218419..7236809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005303042.3 → XP_005303099.1  adenine DNA glycosylase isoform X3

    Conserved Domains (4) summary
    smart00525
    Location:250 → 270
    FES; iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3)
    COG1194
    Location:53 → 477
    MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
    cd00056
    Location:89 → 247
    ENDO3c; endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases
    cd03431
    Location:340 → 478
    DNA_Glycosylase_C; DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important ...

  2. XM_024103911.2 → XP_023959679.1  adenine DNA glycosylase isoform X1

    Conserved Domains (1) summary
    COG1194
    Location:83 → 507
    MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]

  3. XM_042845050.1 → XP_042700984.1  adenine DNA glycosylase isoform X2

    Conserved Domains (1) summary
    COG1194
    Location:83 → 505
    MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]

  4. XM_042845051.1 → XP_042700985.1  adenine DNA glycosylase isoform X4

    Conserved Domains (1) summary
    COG1194
    Location:83 → 469
    MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]

  5. XM_024103913.2 → XP_023959681.1  adenine DNA glycosylase isoform X5

    Conserved Domains (1) summary
    COG1194
    Location:16 → 440
    MutY; Adenine-specific DNA glycosylase, acts on AG and A-oxoG pairs [Replication, recombination and repair]
Nucleotide Protein
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