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NRG1 neuregulin 1 [ Falco peregrinus (peregrine falcon) ]

Gene ID: 101924430, updated on 8-Mar-2024

Summary

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Gene symbol
NRG1
Gene description
neuregulin 1
See related
EnsemblRapid:ENSFPEG00020010678
Gene type
protein coding
RefSeq status
MODEL
Organism
Falco peregrinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Falconiformes; Falconidae; Falco
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Z
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_04 current bFalPer1.pri (GCF_023634155.1) Z NC_073739.1 (31852866..32159729, complement)
102 previous assembly F_peregrinus_v1.0 (GCF_000337955.1) Unplaced Scaffold NW_004929928.1 (4329884..4636846, complement)

Chromosome Z - NC_073739.1Genomic Context describing neighboring genes Neighboring gene protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha-like Neighboring gene fucosyltransferase 10 Neighboring gene uncharacterized LOC129782794 Neighboring gene uncharacterized LOC129782748 Neighboring gene lipoprotein lipase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chemorepellent activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pro-neuregulin-1, membrane-bound isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_023634155.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bFalPer1.pri Primary Assembly

Genomic

  1. NC_073739.1 Reference bFalPer1.pri Primary Assembly

    Range
    31852866..32159729 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013295510.3 → XP_013150964.1  pro-neuregulin-1, membrane-bound isoform isoform X2

    Related
    ENSFPEP00020016009.1, ENSFPET00020016489.1
    Conserved Domains (4) summary
    cd05895
    Location:12 → 87
    Ig_Pro_neuregulin-1; Immunoglobulin (Ig)-like domain found in neuregulin (NRG)-1
    cd00054
    Location:116 → 148
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07679
    Location:2 → 89
    I-set; Immunoglobulin I-set domain
    pfam02158
    Location:166 → 557
    Neuregulin; Neuregulin family

  2. XM_005232837.3 → XP_005232894.1  pro-neuregulin-1, membrane-bound isoform isoform X1

    Related
    ENSFPEP00020015915.1, ENSFPET00020016395.1
    Conserved Domains (2) summary
    cd00054
    Location:232 → 264
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam02158
    Location:282 → 673
    Neuregulin; Neuregulin family

  3. XM_055791616.1 → XP_055647591.1  pro-neuregulin-1, membrane-bound isoform isoform X3

    Related
    ENSFPEP00020015929.1, ENSFPET00020016409.1
Nucleotide Protein
Heading Accession and Version

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