These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_030586.1 RefSeqGene
- Range
- 5001..28758
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001018003.2 → NP_001018003.1 vinexin isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) has multiple differences in the presence and absence of exons at its 5' end, compared to variant 1. These differences produce a unique 5' UTR and cause translation initiation at a downstream start codon, compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1.
- Source sequence(s)
-
BC010146, BM999851, CX783871
- Consensus CDS
-
CCDS47824.1
- UniProtKB/Swiss-Prot
-
O60504
- Related
- ENSP00000408476, ENST00000428103
- Conserved Domains (1) summary
-
- cd00174
Location:46 – 94
Blast Score: 161
- SH3; Src homology 3 domains; SH3 domains bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs; they play a role in the regulation of enzymes by intramolecular interactions, changing the subcellular localization of ...
-
NM_005775.4 → NP_005766.3 vinexin isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
- Source sequence(s)
-
AF037261, BC091514, BM999851, CF456833
- Consensus CDS
-
CCDS6031.1
- UniProtKB/Swiss-Prot
-
O60504
- Related
- ENSP00000240123, OTTHUMP00000162521, ENST00000240123, OTTHUMT00000254647
- Conserved Domains (2) summary
-
- cd00174
Location:388 – 436
Blast Score: 162
- SH3; Src homology 3 domains; SH3 domains bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs; they play a role in the regulation of enzymes by intramolecular interactions, changing the subcellular localization of ...
- cl02617
Location:116 – 165
Blast Score: 219
- Sorb; Sorbin homologous domain
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000008.10 Reference GRCh37.p5 Primary Assembly
- Range
- 22409251..22433008
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000140.1 Alternate HuRef
- Range
- 20951413..20975170
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)