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Phf12 PHD finger protein 12 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101721891, updated on 8-Mar-2024

Summary

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Gene symbol
Phf12
Gene description
PHD finger protein 12
Locus tag
GW7_08193
See related
Ensembl:ENSHGLG00000008718
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624786.1 (1472111..1517916, complement)

NW_004624786.1Genomic Context describing neighboring genes Neighboring gene flotillin 2 Neighboring gene dehydrogenase/reductase 13 Neighboring gene cytochrome c-like Neighboring gene seizure related 6 homolog Neighboring gene pipecolic acid and sarcosine oxidase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624786 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Sin3-type complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
PHD finger protein 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624786.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    1472111..1517916 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004857034.3 → XP_004857091.1  PHD finger protein 12 isoform X1

    UniProtKB/TrEMBL
    A0A0P6JUT2, G5BVJ1
    Related
    ENSHGLP00000012194.1, ENSHGLT00000012328.1
    Conserved Domains (4) summary
    cd00060
    Location:813 → 868
    FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
    cd15533
    Location:58 → 102
    PHD1_PHF12; PHD finger 1 found in PHD finger protein 12 (PHF12)
    cd15534
    Location:273 → 318
    PHD2_PHF12_Rco1; PHD finger 2 found in PHD finger protein 12 (PHF12), yeast Rco1, and similar proteins
    pfam16737
    Location:203 → 241
    PHF12_MRG_bd; PHD finger protein 12 MRG binding domain

  2. XM_021238225.1 → XP_021093884.1  PHD finger protein 12 isoform X2

    Conserved Domains (3) summary
    cd15533
    Location:58 → 102
    PHD1_PHF12; PHD finger 1 found in PHD finger protein 12 (PHF12)
    cd15534
    Location:273 → 318
    PHD2_PHF12_Rco1; PHD finger 2 found in PHD finger protein 12 (PHF12), yeast Rco1, and similar proteins
    pfam16737
    Location:203 → 241
    PHF12_MRG_bd; PHD finger protein 12 MRG binding domain
Nucleotide Protein
Heading Accession and Version

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